Outbreak of tuberculosis in a Stockholm nursery affects 35 children

Berggren-Palme, Ingela; Larsson, Lars-Olaf; Zedenius, Inger; Gillman, Anna; Bennet, Rutger

doi:10.2807/esw.10.43.02823-en

Cited by 6 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We believe that the data from our recent outbreak suggest that any such transition should be undertaken with caution. Two very similar outbreaks involving large numbers of vulnerable children occurred in Western Europe prior to that reported here7 8 and other outbreaks are likely in the future, particularly as migration from TB endemic areas of Europe and the developing world is increasingly facilitated. Additionally, the protective effect of BCG demonstrated here adds to the evidence supporting widespread BCG vaccination in developing countries with high TB prevalence.…”

Section: Discussionmentioning

confidence: 56%

BCG protects toddlers during a tuberculosis outbreak

Gaensbauer

Vandaleur

O’Neil

et al. 2009

Archives of Disease in Childhood

View full text Add to dashboard Cite

In 2007, an outbreak of tuberculosis occurred in a toddler population attending two child care centres in Cork, Ireland. Of 268 children exposed, 18 were eventually diagnosed with active tuberculosis. We present the initial clinical and radiographic characteristics of the active disease group. Mantoux testing was positive in only 66% of cases. All cases were either pulmonary or involved hilar adenopathy on chest radiograph; there were no cases of disseminated disease or meningitis. 24% of the exposed children had been previously vaccinated with BCG, and no case of active disease was found in this group (p = 0.016), suggesting a profound protective effect of BCG in this population. Our experience provides evidence supporting a protective effect of BCG against pulmonary disease in young children.

show abstract

Section: Discussionmentioning

confidence: 56%

BCG protects toddlers during a tuberculosis outbreak

Gaensbauer

Vandaleur

O’Neil

et al. 2009

Archives of Disease in Childhood

View full text Add to dashboard Cite

show abstract

“…4 The spectrum of clinical manifestations was similar to descriptions in classic studies from the prechemotherapy era. 5,6 Treatment was complicated because of isoniazid resistance, but was eventually completed by all children.…”

Section: Discussionmentioning

confidence: 59%