Outcome After Mechanical Aortic Valve Replacement in Children and Young Adults

Arnold, Raoul; Ley‐Zaporozhan, Julia; Ley, Sebastian; Loukanov, Tsvetomir; Sebening, Christian; Kleber, Johann-Baptist; Goebel, Björn; Hagl, S.; Kretzler, Matthias; Gorenflo, Matthias

doi:10.1016/j.athoracsur.2007.10.035

Cited by 20 publications

(6 citation statements)

References 25 publications

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“…Our data are almost identical to those reported by Alexiou and associates (5) and Arnold and coworkers (12) concerning the cardiovascular events. In one case, we found subaortic stenosis in a patient who required a second operation after mechanical AVR.…”

Section: Mechanical Aortic Valve Replacement In Children Adolescentssupporting

confidence: 92%

“…We surgically address this lesion when the systolic peak gradient reaches 50 mm Hg, or with any evidence of AV insufficiency detected by echocardiography to avoid progressive left ventricular hypertrophy and dilatation (19). Our incidence of postoperative complete heart block requiring a permanent pacemaker implantation (3.7%) is similar to those found in the literature (12,13). Moreover, one MVR with a mechanical prosthesis due to moderate to severe mitral and one aortocoronary bypass grafting due to stenosis of a coronary artery were performed after mechanical AVR.…”

Section: Mechanical Aortic Valve Replacement In Children Adolescentssupporting

confidence: 67%

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Mechanical Aortic Valve Replacement in Children and Adolescents After Previous Repair of Congenital Heart Disease

Popov¹,

Coskun²,

Tirilomis³

et al. 2009

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Due to improved outcome after surgery for congenital heart defects, children, adolescents, and grown-ups with congenital heart defects become an increasing population. In order to evaluate operative risk and early outcome after mechanical aortic valve replacement (AVR) in this population, we reviewed patients who underwent previous repair of congenital heart defects. Between July 2002 and November 2008, 15 (10 male and 5 female) consecutive patients (mean age 14.5 +/- 10.5 years) underwent mechanical AVR. Hemodynamic indications for AVR were aortic stenosis in four (27%), aortic insufficiency in eight (53%), and mixed disease in three (20%) after previous repair of congenital heart defects. All patients had undergone one or more previous cardiovascular operations due to any congenital heart disease. Concomitant cardiac procedures were performed in all of them. In addition to AVR, in two patients, a mitral valve exchange was performed. One patient received a right ventricle-pulmonary artery conduit replacement as concomitant procedure. The mean size of implanted valves was 23 mm (range 17-29 mm). There were neither early deaths nor late mortality until December 2008. Reoperations were necessary in five (33%) and included implantation of a permanent pacemaker due to complete atrioventricular block in two (15%), mitral valve replacement with a mechanical prosthesis due to moderate to severe mitral regurgitation in one (7%), aortocoronary bypass grafting due to stenosis of a coronary artery in one (7%), and in one (7%), a redo subaortic stenosis resection was performed because of a secondary subaortic stenosis. At the latest clinical evaluation, all patients were in good clinical condition without a pathological increased gradient across the aortic valve prosthesis or paravalvular leakage in echocardiography. Mechanical AVR has excellent results in patients after previous repair of congenital heart defects in childhood, even in combination with complex concomitant procedures. Previous operations do not significantly affect postoperative outcome.

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Section: Mechanical Aortic Valve Replacement In Children Adolescentssupporting

confidence: 92%

Section: Mechanical Aortic Valve Replacement In Children Adolescentssupporting

confidence: 67%

Mechanical Aortic Valve Replacement in Children and Adolescents After Previous Repair of Congenital Heart Disease

Popov¹,

Coskun²,

Tirilomis³

et al. 2009

Artificial Organs

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“…13 Aortic valve replacement when performed in a timely fashion, even in children and young adults has been shown to offer good clinical outcomes and may lead to normalization of left ventricular size and function in most patients. 11 However, surgery cannot be delayed too long after which the potential benefits of surgery are lost and the myocardial injury cannot be reversed. Extreme LV dilation (LVEDD >4 SD) (n = 18) 5 (28%)* 5 (28%) (P = .09) 0 (0%) 3 (17%) LV dysfunction (LV SF <28%) (n = 3) 0 (0%) 1 (33%) 2 (67%)** 3 (100%)** LVESD >4 SD (n = 14)…”

Section: Discussionmentioning

confidence: 99%

“…There is a paucity of data in the pediatric age group to determine optimal timing of surgery in patients with isolated AR. 11 Our aim is to identify the risk factors that could predict postoperative outcome after aortic valve replacement in pediatric patients.…”

Section: Introductionmentioning

confidence: 99%

Predictors of Left Ventricular Remodeling after Aortic Valve Replacement in Pediatric Patients with Isolated Aortic Regurgitation

Buddhe

Walters

et al. 2012

Congenital Heart Disease

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“…3 A growing body of literature has elucidated an association between facility case volume and improved patient outcomes for both oncologic 4,5 and non-oncologic conditions. 6–8 Such volume-outcomes studies in patients with STS are limited. 9 Therefore, we assessed a large modern cohort of patients using a nationwide cancer registry to explore the relationship between facility case volume and overall survival (OS) in STS.…”

Section: Introductionmentioning

confidence: 99%

Association Between Treatment at High-Volume Facilities and Improved Overall Survival in Soft Tissue Sarcomas

Venigalla

Nead

Sebro

et al. 2018

International Journal of Radiation Oncology*Biology*Physics

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In this observational cohort study using the National Cancer Database, receipt of surgery and radiation therapy at HV facilities was associated with improved OS in patients with STS. Potential sociodemographic disparities limit access to care at HV facilities for certain populations. Our findings highlight the importance of receipt of care at HV facilities for patients with STS and warrant further study into improving access to care at HV facilities.

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Outcome After Mechanical Aortic Valve Replacement in Children and Young Adults

Cited by 20 publications

References 25 publications

Mechanical Aortic Valve Replacement in Children and Adolescents After Previous Repair of Congenital Heart Disease

Mechanical Aortic Valve Replacement in Children and Adolescents After Previous Repair of Congenital Heart Disease

Predictors of Left Ventricular Remodeling after Aortic Valve Replacement in Pediatric Patients with Isolated Aortic Regurgitation

Association Between Treatment at High-Volume Facilities and Improved Overall Survival in Soft Tissue Sarcomas

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