Outcome and complications of reconstruction of the thoracolumbar spine for vertebral tumours

Viñas, Federico C.; King, Paul; Holdener, Hansjurg; Dulchavsky, Scott A.; Díaz, Fernando G.

doi:10.1016/s0967-5868(99)90002-4

Cited by 2 publications

(3 citation statements)

References 21 publications

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“…Different observational studies have reported an average blood loss ranging from 1,360 cc to 3,145 cc during corpectomies or en bloc tumorectomies of the thoracic or cervicothoracic region. However, massive blood loss has also been reported with maximum blood losses of 21,000 cc [38][39][40][41][42][43] (Table 1). Combined anterior-posterior thoracic corpectomies are associated with a higher blood loss than anterior or posterior only approaches [41].…”

Section: Oncological Spine and Sacral Surgerymentioning

confidence: 99%

“…Reported estimated blood loss [38][39][40][41][42][43] 400-12,100 2-10 Sacral tumors [44][45][46] 3,000-37,000 0-43 Hemipelvectomy [47][48][49][50] 400-12,100 0-134 Total pelvic exenterations [47][48][49][50] 900-9,500 0-18 Nephrectomy with IVC embolectomy [37,[51][52][53][54][55] 200−16,000 0−91 Liver and multivisceral resection [12,[56][57][58][59][60][61][62] 200->5,000 0-44 Extrapleural pneumonectomies [63][64][65] 900-65,00 0-18 Table 1 illustrates ranges of blood losses and PRBCs of transfused units reported in the literature.…”

Section: Nephrectomy With Inferior Venous Cava Thrombectomymentioning

confidence: 99%

“…However, most studies report that the rate ranges from 17% to 70% [43]. The median number of PRBC units transfused during lumbar surgery for metastatic disease is 2 units; however, an unknown number of patients still receive more than 10 units of packed red cells [42].…”

Section: Oncological Spine and Sacral Surgerymentioning

confidence: 99%

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Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery: What Do We Know?

Cata

Gottumukkala

2012

ISRN Anesthesiology

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Patients with solid malignancies who were not candidates for tumor resections in the past are now presenting for extensive oncological resections. Cancer patients are at risk for thromboembolic complications due to an underlying hypercoagulable state; however, some patients may have an increased risk for bleeding due to the effects of chemotherapy, the administration of anticoagulant drugs, tumor-related fibrinolysis, tumor location, tumor vascularity, and extent of disease. A common potential complication of all complex oncological surgeries is massive intra-and postoperative hemorrhage and the subsequent risk for massive blood transfusion. This can be anticipated or unexpected. Several surgical and anesthesia interventions including preoperative tumor embolization, major vessel occlusion, hemodynamic manipulation, and perioperative antifibrinolytic therapy have been used to prevent or control blood loss with varying success. The exact incidence of massive blood transfusion in oncological surgery is largely unknown and/or underreported. The current literature mostly consists of purely descriptive observational studies. Thus, recommendation regarding specific perioperative intervention cannot be made at this point, and more research is warranted.

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