Outcome and etiologies of fetal megacystis according to the gestational age at diagnosis

“…Bornes ve ark.nın yaptığı ve 84 fetüsü değerlendirdikleri retrospektif çalışmada, ilk trimesterde megasistis saptanan hiçbir fetüs yaşamamıştır. 8 Bizim olgularda gebelik terminasyon oranı tüm olgular alındığında %48,2, bu fetüslerin intrauterin kayıp oranları ise %13,7 olarak saptandı. İzole megasistis olgularında terminasyon oranı %42,8, intrauterin kayıp oranı ise %19 olarak saptandı.…”

Section: Discussionunclassified

Prognosis of Diagnosed Megacyctis in the First Trimester Fetus at Our Clinic

Comba¹,

Kalelioğlu²,

Esmer³

et al. 2015

Turkiye Klinikleri J Gynecol Obst

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“…Indeed, while in the first trimester, LUTO is mainly due to stenosis or atresia [20,23,26]; in the second or third trimester it (or LUTO?) is mainly due to PUV [8,19,25,27,28]. Another important etiology of LUTO is PBS, characterized by MC always associated with other malformations (urogenital tract and abdominal muscle hypoplasia).…”

Section: Discussionmentioning

confidence: 99%

Fetal Megacystis: Experience of a Single Tertiary Center in Switzerland over 20 Years

Brochut¹,

Thomann²,

Kluwe

et al. 2014

Fetal Diagn Ther

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Objectives: Megacystis (MC) is rare and often associated with other structural and chromosomal anomalies. In euploid cases with early oligohydramnios, prognosis is poor mainly due to pulmonary hypoplasia and renal damage. We report our experience of the past 20 years. Methods: A retrospective review of cases with prenatally diagnosed MC was performed. Complete prenatal as well as postnatal medical records from 1989 to 2009 were reviewed focusing on diagnostic precision, fetal interventions [vesicocentesis (VC), vesicoamniotic shunt (VAS)], short- and long-term outcome, and potential prognostic factors. Results: 68 cases were included. Follow-up was available in 54 cases (9 girls and 45 boys including 3 cases with aneuploidy). We found 39 isolated MC at sonography (5 girls and 34 boys). 24 fetuses with isolated MC underwent VC and VAS at 19.6 ± 6.3 and 20 ± 4.9 weeks of gestation, respectively. Survival rate was higher in male than in female fetuses (51 vs. 33%). Renal problems occurred in 4/14 prenatally treated fetuses and in 1/10 when cases with prune belly syndrome (PBS) were excluded from the analysis. Conclusions: Our study shows that a careful selection of cases with MC excluding fetuses with PBS and early treatment has still the potential to improve outcome.

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Outcome and etiologies of fetal megacystis according to the gestational age at diagnosis

Cited by 42 publications

References 18 publications

Types and Outcome of Fetal Urinary Anomalies in Low Resource Setting Countries: A Retrospective Study

Types and Outcome of Fetal Urinary Anomalies in Low Resource Setting Countries: A Retrospective Study

Prognosis of Diagnosed Megacyctis in the First Trimester Fetus at Our Clinic

Fetal Megacystis: Experience of a Single Tertiary Center in Switzerland over 20 Years

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