Outcome Following Surgery for Primary Lung Cancer with Interlobar Pleural Invasion

Nonaka, Makoto; Kataoka, Daisuke; Yamamoto, Shigeru; Horichi, Naoya; Ohgiya, Yoshimitsu; Kushima, Miki; Kunimura, Toshiaki; Takaba, Toshihiro

doi:10.1007/s00595-004-2894-2

Cited by 19 publications

(23 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Normally, VPI indicates biological tumor invasiveness and is associated with a poor outcome. 3,4,7,9 Although we evidenced a pN0 rate of 58%, other authors reported that pN0 is generally inferior to 50% of cases, whereas nodal involvement is present in more than twothird of patients as a result of drainage of invading tumor into the adjacent lobe lymphatic system. By penetrating two different layers of the visceral pleura, tumors invading the fissure have a high probability to invade small lymphatic ducts and blood vessels.…”

Section: Discussioncontrasting

confidence: 52%

“…In our series, these patients were associated with a greater pathological tumor size. Okada et al, 4 Nonaka et al, 9 and Haam et al 10 have reported that survival did not differ between the patients receiving a lobectomy with the partial resection and those receiving an anatomical resection. 14 2.…”

Section: Discussionmentioning

confidence: 97%

“…Previous works on interlobar spread of NSCLC have resulted in highly variable conclusions. In a series of 50 patients, Nonaka et al 9 reported a 5-year OS of 63%. On the contrary, Okada et al 4 and Demir et al 7 suggested that NCSLC with FI had similar survival to that of T3 tumors.…”

Section: Discussionmentioning

confidence: 97%

See 2 more Smart Citations

Surgical Treatment in Patient with Non–Small-Cell Lung Cancer with Fissure Involvement: Anatomical versus Nonanatomical Resection

Leuzzi

Cesario

Cafarotti

et al. 2014

Journal of Thoracic Oncology

View full text Add to dashboard Cite

Our results suggest that nonanatomical resection (LWR) could be considered as a feasible surgical option (especially in "frail" patients with an extent of FI less than 3 cm) in the light of the similar oncological and functional outcome compared with anatomical resection. Further studies based on larger series are needed to confirm these preliminary data and also to investigate the impact on the postoperative quality of life.

show abstract

Section: Discussioncontrasting

confidence: 52%

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Surgical Treatment in Patient with Non–Small-Cell Lung Cancer with Fissure Involvement: Anatomical versus Nonanatomical Resection

Leuzzi

Cesario

Cafarotti

et al. 2014

Journal of Thoracic Oncology

View full text Add to dashboard Cite

show abstract

“…Riquet and colleagues 13 reported NSCLC with such a fissure invasion to an adjacent lobe was an independent factor of poor prognosis as well as visceral pleura invasion. Nonaka et al 14 found the five-year survival rate of 28 patients with squamous cell carcinomas in cases of adjacent lobe invasion was similar to that of T2 disease and thus concluded that tumors with adjacent lobe invasion should be classified as T2 in squamous cell carcinoma. Ohtaki and colleagues 15 divided lung cancer with such a fissure invasion into the invasion across complete and incomplete fissure and found the complete fissure was associated with a better prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…Different lymph node status was included in previously reported studies in which the effect of lymph node involvement on survival was not excluded 5,6,14 . Therefore, the conclusion of T category was still controversial.…”

Section: Discussionmentioning

confidence: 99%

T category of non–small cell lung cancer invading the fissure to the adjacent lobe

Liu

Wigle²,

Wampfler³

et al. 2017

The Journal of Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

Background Dispute arises in the tumor category of non-small cell lung cancer (NSCLC) invading the fissure to the adjacent lobe. The purpose of this study is to determine the long-term prognosis of NSCLC with such an invasion and to propose an appropriate T category. Methods In total, 53 cases of NSCLC invading the fissure to the adjacent lobe (Fissure group) was identified in patients that underwent pulmonary resection from 1997 through 2014. Propensity score matching was applied to balance known confounders for prognosis between each paired group, resulting in three matched sets (Fissure vs. T2a, Fissure vs. T2b, and Fissure vs. T3). The overall survival of the Fissure group was compared to those of patients with T2a, T2b, and T3 diseases, as classified in the eighth edition of TNM classification. Results The 5-years survival rates of T2a, T2b, T3 and the Fissure group were 64.2% (95% confidence interval, 53.2–72.6), 54.6% (95% confidence interval, 44.7–65.8), 35.8% (95% confidence interval, 22.8–44.2) and 38.6% (95% confidence interval, 25.0–52.2), respectively. Specifically, the difference between the Fissure group and T2a is statistically significant, p=0.01; between the Fissure group and T2b, p=0.02; and between the Fissure group and T3, p=0.93. Multivariate analyses indicate the Fissure group had a similar risk of dying as the T3 disease (Hazard ratio 1.10, 95% confidence interval 0.69–1.37) and was at a significantly higher risk compared to the T2a (Hazard ratio 2.34, 95% confidence interval 1.50–3.39) and T2b diseases (Hazard ratio 1.71, 95% confidence interval 1.19–2.76 ). Conclusions Based on our single-institution study, we propose that NSCLC invading the fissure to the adjacent lobe should be further investigated and the impact on patient’s prognosis validated as a T3 disease.

show abstract

Adjacent lobe invasion of T2 tumor in non-small cell lung cancer has T3 disease-like survival fissure invasion: T2 or T3?

et al. 2023

View full text Add to dashboard Cite

Outcome Following Surgery for Primary Lung Cancer with Interlobar Pleural Invasion

Cited by 19 publications

References 7 publications

Surgical Treatment in Patient with Non–Small-Cell Lung Cancer with Fissure Involvement: Anatomical versus Nonanatomical Resection

Surgical Treatment in Patient with Non–Small-Cell Lung Cancer with Fissure Involvement: Anatomical versus Nonanatomical Resection

T category of non–small cell lung cancer invading the fissure to the adjacent lobe

Adjacent lobe invasion of T2 tumor in non-small cell lung cancer has T3 disease-like survival fissure invasion: T2 or T3?

Contact Info

Product

Resources

About