Outcome in Patients Who Require Venoarterial Extracorporeal Membrane Oxygenation Support After Cardiac Surgery

Elsharkawy, Hesham; Li, Liang; Esa, Wael Ali Sakr; Sessler, Daniel I.; Bashour, C. Allen

doi:10.1053/j.jvca.2010.03.020

Cited by 119 publications

(74 citation statements)

References 22 publications

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“…5,6,7,9,10 However, there remains limited data from previous studies to suggest which patients make good candidates for cardiac ECMO, and which patients are futile cases. While previous studies have determined various risk factors for cardiac ECMO patients, no studies to date have isolated a specific risk score for this patient population.…”

Section: Discussionmentioning

confidence: 99%

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Simple new risk score model for adult cardiac extracorporeal membrane oxygenation: simple cardiac ECMO score

Peigh

Cavarocchi

Keith

et al. 2015

Journal of Surgical Research

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Section: Discussionmentioning

confidence: 99%

“…7,5,9,10 With the use of ECMO for patient salvage from refractory cardiogenic shock in adult populations increasing exponentially, a comprehensive analysis of risk factors associated with the treatment, with the aim of creating a simple risk model, has yet to be completed.…”

Section: Introductionmentioning

confidence: 99%

Simple new risk score model for adult cardiac extracorporeal membrane oxygenation: simple cardiac ECMO score

Peigh

Cavarocchi

Keith

et al. 2015

Journal of Surgical Research

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“…260 For patients with a potentially reversible cause of their CS (eg, acute fulminant myocarditis), outcomes are even better, whereas those with postcardiotomy CS do considerably worse. 261,262 There are no randomized trials assessing the effectiveness of ECMO systems.…”

Section: Extracorporeal Membrane Oxygenationmentioning

confidence: 99%

Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association

Diepen¹,

Katz²,

Albert³

et al. 2017

Circulation

1,349

1,165

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Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state of end-organ hypoperfusion that is frequently associated with multisystem organ failure. Despite improving survival in recent years, patient morbidity and mortality remain high, and there are few evidence-based therapeutic interventions known to clearly improve patient outcomes. This scientific statement on cardiogenic shock summarizes the epidemiology, pathophysiology, causes, and outcomes of cardiogenic shock; reviews contemporary best medical, surgical, mechanical circulatory support, and palliative care practices; advocates for the development of regionalized systems of care; and outlines future research priorities. Cardiogenic shock (CS) is a low-cardiac-output state resulting in life-threatening end-organ hypoperfusion and hypoxia.1,2 Acute myocardial infarction (MI) with left ventricular (LV) dysfunction remains the most frequent cause of CS. 1,3 Advances in reperfusion therapy have been associated with improvements in survival, but significant regional disparities in evidence-based care have been reported, and in-hospital mortality remains high (27%-51%).1,4-9 Management recommendations are distributed between disease-specific statements and guidelines, and a dedicated and comprehensive clinical resource in this area is lacking. Thus, consolidating the evidence to define contemporary best medical and surgical CS practices for both MI-associated CS and other types of CS may be an important step in knowledge translation to help attenuate disparities in evidence-based care.Regional systems of care coupled with treatment algorithms have improved survival in high-acuity time-sensitive conditions such as MI, out-of-hospital cardiac arrest (OHCA), and trauma.10-12 Applying a similar framework to CS management may lead to similar improvements in survival, and CS systems of care are emerging within existing regional cardiovascular emergency care networks; however, guidance from a national expert group on structure and systems of care has not been available. 13,14 Accordingly, the purposes of this American Heart Association (AHA) scientific statement on CS are to summarize our contemporary understanding of the epidemiology, pathophysiology, and in-hospital best care practices into a single clinical resource document; to suggest a stepwise management algorithm that integrates medical, surgical, and mechanical circulatory support (MCS) therapies; and to propose a Mission: Lifelinesupported pathway for the development of integrated regionalized CS systems of care. DEFINITION OF CSAcute cardiac hemodynamic instability may result from disorders that impair function of the myocardium, valves, conduction system, or pericardium, either in isolation HISTORICAL PERSPECTIVESBefore the routine use of early revascularization, MIassociated CS had an in-hospital mortality exceeding 80%. A registry trial of 250 patients with acute MI described the association between bedside physical examination (Killip classification) for the as...

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“…A single institution series evaluating outcomes of VA-ECLS in the post-cardiac surgery setting in 233 patients demonstrated a lower survival rate to hospital discharge of 36% (7). A study comparing outcomes between 321 patients receiving conventional cardiopulmonary resuscitation and 85 patients receiving VA-ECLS in the setting of witnessed cardiac arrest demonstrated significantly improved hospital survival and 6-month survival with none or minimal neurologic impairment in the VA-ECLS group, particularly in cases of cardiac origin.…”

Section: Discussionmentioning

confidence: 99%

Initiation and management of adult veno-arterial extracorporeal life support

et al. 2017

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Outcome in Patients Who Require Venoarterial Extracorporeal Membrane Oxygenation Support After Cardiac Surgery

Cited by 119 publications

References 22 publications

Simple new risk score model for adult cardiac extracorporeal membrane oxygenation: simple cardiac ECMO score

Simple new risk score model for adult cardiac extracorporeal membrane oxygenation: simple cardiac ECMO score

Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association

Initiation and management of adult veno-arterial extracorporeal life support

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