Outcome Measures After Sclerotherapy of Venous Malformations: A Systematic Review

Asdahl, Kristina R.; Hedelund, Lene; Keller, Johnny; Baad‐Hansen, Thomas; Damsgaard, Tine Engberg

doi:10.1007/s00270-018-1919-y

Cited by 13 publications

(9 citation statements)

References 48 publications

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“…There is no clear method to evaluate the outcomes of sclerotherapy for VM. 17 Several publications report there is a discrepancy between radiologic and clinical outcomes after VM sclerotherapy. 7,[11][12][13]18 Bianchini, G et al reported significant improvement in the symptoms in intramuscular VMs with sclerotherapy even when 83.9% of the posttreatment MRI showed no significant change of the VMs.…”

Section: Discussionmentioning

confidence: 99%

Clinical results of polidocanol sclerotherapy in venous malformation treatment: Patient-perceived improvement and satisfaction

et al. 2022

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Purpose This study evaluated the results of polidocanol sclerotherapy in the treatment of venous malformations (VM) including patient satisfaction, perceived improvement, and predictors of satisfaction. Material and Method Patients with VM that underwent polidocanol foam sclerotherapy between June 2013 and July 2021 in a single center were retrospectively evaluated. Patient demographics, VM, and treatment characteristics were analyzed. Patient-reported outcomes and satisfaction were analyzed with a questionnaire. Results This study included 232 (136, 58.6%, female) patients. The mean age was 24.49 ± 12.45 years (range 3–72). The clinical response rate was 82.3%. The rate of satisfaction was 82.3%, and 116 (50%) patients were significantly satisfied. There were no major complications. Clinical response and VM margin were related to satisfaction ( p < 0.01, p = 0.012, respectively). Clinical response to pretreatment swelling was related to significant satisfaction ( p = 0.02). Conclusion Polidocanol sclerotherapy was safe and effective in VM treatment with high satisfaction and low complication rates.

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Section: Discussionmentioning

confidence: 99%

Clinical results of polidocanol sclerotherapy in venous malformation treatment: Patient-perceived improvement and satisfaction

et al. 2022

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“…The evaluation of outcome measurements for vascular malformations is limited by the quality of available literature, with wide range of excellent (8%-95%), good (11%-90%), and poor (5%-16%) results. 23 De Maria et al 24…”

Section: Discussionmentioning

confidence: 99%

“…The evaluation of outcome measurements for vascular malformations is limited by the quality of available literature, with wide range of excellent (8%–95%), good (11%–90%), and poor (5%–16%) results 23 . De Maria et al 24 published a systematic review of sclerotherapy agents used for VMs of the face, head, and neck.…”

Section: Discussionmentioning

confidence: 99%

Intralesional therapies for vascular malformations of the head and neck

Wadhwa

Pua

Kadenhe-Chiweshe

et al. 2022

J Oral Pathology Medicine

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Vascular malformations in the head and neck region are complex anomalies that represent a diagnostic and therapeutic dilemma for treating physicians. These lesions are divided into fast and slow flow lesions. The most common fast flow lesion encountered in the head and neck is the arteriovenous malformation (AVM). Slow flow malformations are comprised of venous (VM), lymphatic (LM), or lymphatic-venous malformations (LVMs). LMs are often classified as macrocystic, microcystic, or mixed, a pertinent feature when determining suitability for intralesional therapy. Vascular malformations are often best managed by a multidisciplinary team of surgeons (general, otolaryngology, plastics, and orthopedics), dermatologists, hematologists, diagnostic, and interventional radiologists and geneticists, where indicated such as in syndromic cases. Diagnosis is usually made based on a combination of factors: prenatal imaging, age of presentation, clinical appearance and course, and imaging with ultrasound and MRI, as this modality serves as the gold standard imaging technique for these malformations. Indications for treatment are largely dependent on whether the malformation has impact on life, function, or cosmesis, as determined by presentation.Symptoms can range from life-threatening such as stridor due to airway obstruction, to pain, swelling, disfigurement, infections, bleeding, and consumptive coagulopathy. Surgical resection is a rea-

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“…stated that the past literature shows no clear method to evaluate the effect of sclerotherapy. 12 They also expressed that future studies should be related to anatomic location and depth of the malformation. In this study we compared the treatment results of extra- and intramuscular VM’s after Polidocanol sclerotherapy with the patient’s subjective evaluation of the outcome and QOL after the treatment.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and clinical results after endovascular sclerotherapy: A comparison between intra- and extramuscular low-flow venous malformations

et al. 2020

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Background Based on clinical observations we hypothesized that patients with intramuscular venous malformations (VMs) did worse or needed more sclerotherapy sessions than patients with extramuscular VMs. Purpose To evaluate the difference in treatment and quality of life (QOL) results after Polidocanol sclerotherapy of intra- and extramuscular low-flow VMs. Material and methods Forty-one patients with a VM were treated with Polidocanol in two university hospitals. The results were retrospectively analyzed. Pre- and post-treatment magnetic resonance imaging (MRI) scans were compared. All patients completed a self-evaluating form on symptoms as well as a QOL questionnaire. The results were compared between two groups: intra- and extramuscular VM’s. Results No statistically significant differences between intra- and extramuscular groups concerning QOL and specific dimensions pain, functional problems or cosmetic appearance were found. Radiological changes in MRI examinations did not correlate with any of the subjective symptoms. 56% of the patients benefitted from the treatment according to patient self-evaluation. Conclusion In this material intramuscular VM’s responded to the treatment comparably to extramuscular malformations. Post-treatment MRI findings do not correlate with subjective symptoms or QOL results and thus, a routine post-treatment examination seems to be unwarranted. Subjective symptoms and QOL results are the most important parameters in evaluating the effectiveness of sclerotherapy.

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Outcome Measures After Sclerotherapy of Venous Malformations: A Systematic Review

Abstract: The published literature over the past 10 years shows no clear method to evaluate the effect of sclerotherapy for venous malformation. We suggest that a standard set of outcome measures should be defined.

Cited by 13 publications

References 48 publications

Clinical results of polidocanol sclerotherapy in venous malformation treatment: Patient-perceived improvement and satisfaction

Clinical results of polidocanol sclerotherapy in venous malformation treatment: Patient-perceived improvement and satisfaction

Intralesional therapies for vascular malformations of the head and neck

Quality of life and clinical results after endovascular sclerotherapy: A comparison between intra- and extramuscular low-flow venous malformations

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