Outcome of 100 vestibular schwannomas managed conservatively in a 10-year study

Kishore, Ameet; Hadoura, Lubna; Crowther, John A.; O’Reilly, Brian V.

doi:10.1016/s0194-5998(03)01221-x

Cited by 2 publications

(1 citation statement)

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“…We identified 21 eligible studies published between 1989 and 2003, comprising 1,345 patients 1–21 . The number of patients in each study ranged from 13 to 123.…”

Section: Resultsmentioning

confidence: 99%

Conservative Management of Acoustic Neuroma: A Meta-Analysis and Proposed Treatment Algorithm

et al. 2005

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Our meta-analysis supports the role of conservative management of acoustic neuromas in properly selected patients on the basis of a slow overall rate of growth and a substantial incidence of no growth. However, the lack of predictive factors, the relatively short duration of follow-up, and the variability of inclusion criteria underscore the need for continued collection of long-term data. An algorithm for acoustic neuroma management is proposed based on initial tumor size, patient age, and hearing status.

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“…We identified 21 eligible studies published between 1989 and 2003, comprising 1,345 patients 1–21 . The number of patients in each study ranged from 13 to 123.…”

Section: Resultsmentioning

confidence: 99%

Conservative Management of Acoustic Neuroma: A Meta-Analysis and Proposed Treatment Algorithm

et al. 2005

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Surgery of the lateral skull base: a 50-year endeavour

Zanoletti¹,

Mazzoni²,

Martini³

et al. 2019

Acta Otorhinolaryngol Ital

101

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SUMMARY Disregarding the widely used division of skull base into anterior and lateral, since the skull base should be conceived as a single anatomic structure, it was to our convenience to group all those approaches that run from the antero-lateral, pure lateral and postero-lateral side of the skull base as “Surgery of the lateral skull base”. “50 years of endeavour” points to the great effort which has been made over the last decades, when more and more difficult surgeries were performed by reducing morbidity. The principle of lateral skull base surgery, “remove skull base bone to approach the base itself and the adjacent sites of the endo-esocranium”, was then combined with function preservation and with tailoring surgery to the pathology. The concept that histology dictates the extent of resection, balancing the intrinsic morbidity of each approach was the object of the first section of the present report. The main surgical approaches were described in the second section and were conceived not as a step-by-step description of technique, but as the highlighthening of the surgical principles. The third section was centered on open issues related to the tumor and its treatment. The topic of vestibular schwannoma was investigated with the current debate on observation, hearing preservation surgery, hearing rehabilitation, radiotherapy and the recent efforts to detect biological markers able to predict tumor growth. Jugular foramen paragangliomas were treated in the frame of radical or partial surgery, radiotherapy, partial “tailored” surgery and observation. Surgery on meningioma was debated from the point of view of the neurosurgeon and of the otologist. Endolymphatic sac tumors and malignant tumors of the external auditory canal were also treated, as well as chordomas, chondrosarcomas and petrous bone cholesteatomas. Finally, the fourth section focused on free-choice topics which were assigned to aknowledged experts. The aim of this work was attempting to report the state of the art of the lateral skull base surgery after 50 years of hard work and, above all, to raise questions on those issues which still need an answer, as to allow progress in knowledge through sharing of various experiences. At the end of the reading, if more doubts remain rather than certainties, the aim of this work will probably be achieved.

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Outcome of 100 vestibular schwannomas managed conservatively in a 10-year study

Cited by 2 publications

References 0 publications

Conservative Management of Acoustic Neuroma: A Meta-Analysis and Proposed Treatment Algorithm

Conservative Management of Acoustic Neuroma: A Meta-Analysis and Proposed Treatment Algorithm

Surgery of the lateral skull base: a 50-year endeavour

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