2008
DOI: 10.1097/tp.0b013e318166ac45
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Outcome of 234 Pregnancies in 140 Renal Transplant Recipients From Five Middle Eastern Countries

Abstract: In the presence of good allograft function, the majority of pregnancies in renal transplant recipients have a good outcome but with increased incidence of preeclampsia, reduced gestational age, and low birth weights. Patients with baseline serum creatinine of above 150 micromol/L have an increased risk of allograft dysfunction resulting from the pregnancy.

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Cited by 34 publications
(17 citation statements)
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“…The latter difference was statistically significant (Table 3). Al Duraihimh et al reported that patients who had a pre-pregnancy serum creatinine of !1.7 mg/dL experienced a decline in renal function with pregnancy more often than those with normal baseline creatinine [12]. Based on our results and current evaluation of renal/graft function, we assume that not only creatinine concentration, but also eGFR, should be taken into consideration before potential conception.…”
Section: Discussionmentioning
confidence: 87%
“…The latter difference was statistically significant (Table 3). Al Duraihimh et al reported that patients who had a pre-pregnancy serum creatinine of !1.7 mg/dL experienced a decline in renal function with pregnancy more often than those with normal baseline creatinine [12]. Based on our results and current evaluation of renal/graft function, we assume that not only creatinine concentration, but also eGFR, should be taken into consideration before potential conception.…”
Section: Discussionmentioning
confidence: 87%
“…These results were again corroborated in a study of 234 pregnancies in 140 renal transplant recipients in the Middle East. Patients with baseline serum creatinine of above 150 m mol/L, however, were found to have an increased risk of allograft dysfunction resulting from the pregnancy [ 130 ] . There does appear to be an increased risk of premature delivery in renal transplant patients, which may be the result of pregnancy-induced hypertension, worsening renal function, or fetal distress [ 127 ] .…”
Section: Resultsmentioning
confidence: 95%
“…Spontaneous abortion, hypertension and preeclampsia, IUGR and prematurity are the main complications reported in the literature [7,8,[18][19][20][21]. The physiopathogenesis of miscarriages could be due to pathological endometrial morphology related to pituitary-gonadal axis dysfunction, which could compromise egg implantation [21].…”
Section: Commentmentioning
confidence: 97%