Outcome of adults with asymptomatic severe aortic stenosis

Avakian, Solange Desirée; Grinberg, Max; Ramires, José Antônio Franchini; Mansur, Antônio de Pádua

doi:10.1016/j.ijcard.2006.12.019

Cited by 19 publications

(11 citation statements)

References 34 publications

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“…Some work is being produced suggesting benefits from earlier intervention but other observers have published data suggesting benefits and safety of the watchful waiting approach (50,53).…”

Section: Aortic Valve Surgerymentioning

confidence: 99%

Almanac 2012 adult cardiac surgery

Bridgewater¹

2013

Anadolu Kardiyol Derg

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This review covers the important publications in adult cardiac surgery in the last few years, including the current evidence base for surgical revascularisation and the use of off-pump surgery, bilateral internal mammary arteries and endoscopic vein harvesting. The changes in conventional aortic valve surgery are described alongside the outcomes of clinical trials and registries for transcatheter aortic valve implantation, and the introduction of less invasive and novel approaches of conventional aortic valve replacement surgery. Surgery for mitral valve disease is also considered, with particular reference to surgery for asymptomatic degenerative mitral regurgitation. (Anadolu Kardiyol Derg 2013; 13: 414-21) ALMANAC series ALMANAC serileri 414

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“…Some work is being produced suggesting benefits from earlier intervention but other observers have published data suggesting benefits and safety of the watchful waiting approach (50,53).…”

Section: Aortic Valve Surgerymentioning

confidence: 99%

Almanac 2012 adult cardiac surgery

Bridgewater¹

2013

Anadolu Kardiyol Derg

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show abstract

“…Some work is being produced suggesting benefits from earlier intervention but other observers have published data suggesting benefits and safety of the watchful waiting approach. [50][51][52][53]…”

Section: Aortic Valve Surgerymentioning

confidence: 99%

Almanac 2012: Adult cardiac surgery: The national society journals present selected research that has driven recent advances in clinical cardiology

Bridgewater¹

2013

Srce i krvni sudovi

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“…A recent prospective study involving 133 asymptomatic patients with a peak transaortic pressure gradient ≥60 mmHg and normal left ventricular systolic function found that only a reduction in ejection fraction over time (but remaining within normal limits) was an independent predictor of symptom onset or sudden cardiac death (P=0.001) [45]. However, in individual patients the clinical utility of this predictor is limited as the change in ejection fraction is small and single measurements of ejection fraction have wide confidence limits.…”

Section: Risk Stratification For Surgical Therapymentioning

confidence: 99%

Management of Asymptomatic Severe Aortic Stenosis

Stewart

Chan²

2009

CCR

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Patients with symptomatic severe aortic stenosis (AS) benefit from aortic valve replacement surgery, but the management of patients with asymptomatic severe AS is more controversial. While cholesterol and angiotensin have been linked to AS progression, we should await the results of ongoing randomized trials before medical therapy to lower cholesterol or inhibit angiotensin can be recommended to limit disease progression. Clinical factors, echocardiographic parameters, valve morphology, exercise stress testing results, and cardiac biomarkers may be useful in identifying patients who will have early development of symptoms during follow-up and require closer monitoring. The risks associated with aortic valve replacement outweigh the benefits in the majority of patients with asymptomatic severe AS.

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Outcome of adults with asymptomatic severe aortic stenosis

Cited by 19 publications

References 34 publications

Almanac 2012 adult cardiac surgery

Almanac 2012 adult cardiac surgery

Almanac 2012: Adult cardiac surgery: The national society journals present selected research that has driven recent advances in clinical cardiology

Management of Asymptomatic Severe Aortic Stenosis

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