Outcome of Fetuses With Clubfeet Diagnosed by Prenatal Sonography

Mammen, Leena; Benson, Carol B.

doi:10.7863/jum.2004.23.4.497

Cited by 47 publications

(35 citation statements)

References 8 publications

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“…11 Anyway, regarding the clubfoot, ultrasound have proven to be the most reliable method of prenatal diagnosis. 9,10,15,18,[20][21][22][23][24] The ability of achieving prenatal diagnosis of clubfoot have increased during the past two decades from about 25% to over 80%. Reports about the risk of false-positive prenatal diagnosis during pregnancy are diverse: the rate of false-positive prenatal diagnosis vary widely from 0 to 40% in isolated clubfoot.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Clubfoot: A Review of Current Available Methodology

et al. 2017

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Background: Clubfoot is one of the most common congenital limb deformities. Prenatal diagnosis of the condition is essential as it can help treat the malformation as early as possible. We reviewed the recent available literature concerning the current methods for prenatal diagnosis of clubfoot. Methods:The following databases were searched from 1966 to 2015: PubMed, OVID, Cochrane, CINAHL, Google scholar and Embase. Results: Out of a total number of 197 retrieved articles, after abstract or title page evaluation, 158 articles not matching the inclusion criteria were excluded. The full text versions of the remaining 39 articles were obtained, and their reference lists screened, with the addition of another 5 full-text articles. Conclusions: Currently, ultrasonography is considered the most reliable method of prenatal diagnosis of clubfoot. Ultrasonographic diagnosis of clubfoot appears more likely between the 18th and the 24th week of pregnancy. Alternative imaging is not indicated. There is no agreement whether to propose foetal karyotyping when isolated clubfoot is diagnosed by prenatal ultrasonography. Early detection of clubfoot should prompt a careful surveillance during pregnancy in order to detect any possible additional abnormalities and, if any of these are detected, invasive testing should be off ered.

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Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Clubfoot: A Review of Current Available Methodology

et al. 2017

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“…33,36-38,44-46. On the other hand, external factors related to development were also considered 6,31,35 and the deformity appears not to develop before the 12 th week of gestation, pursuant to a fetal ultrasonographic study. 47 The consensus concerning the true genetic inheritance pattern has not yet been established, but a multifactorial polygenic inheritance pattern that can be influenced by external factors is suggested 48,49 , with incomplete dominance and variable penetrance. 35 …”

Section: Etiologymentioning

confidence: 99%

Pé torto congênito

Maranho

Volpon

2011

Acta ortop. bras.

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The clubfoot is one of the most common congenital deformities affecting the lower limbs, it still presents controversial aspects regarding etiology and treatment. In spite of its relatively high frequency, the treatment is still challenging, since the long-term aim is achieving an everlasting flexible, plantigrade, pain-free and totally functional foot. The Ponseti method has gained attention and popularity because of its satisfactory results and surgery avoidance. Presently, surgical treatment is indicated only after failure of conservative methods, avoiding extensive soft-tissue release, but performing localized corrections of the deformities, a technique also know as "a la carte" release. The future perspective is based on the knowledge about long-term results and new understanding of the clubfoot etiology, especially in the genetic field, which may eventually be helpful for prognostic and treatment. Level of Evidence: Level II, systematic review.

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“…Several studies have reported on the accuracy of prenatally diagnosed clubfeet [2,5,6,7,8,9], but none have been able to correlate characteristics found on obstetric US to severity at birth. Recently, we described and retrospectively evaluated a novel sonographic severity classification [10].…”

Section: Introductionmentioning

confidence: 99%

“…The ability to counsel patients is dependent upon the accuracy of the prenatal ultrasound (US). Historically, this has been problematic with regard to clubfoot, as the reported false US diagnosis rates range between 0 and 29% in the literature [3,4,5,6,7]. …”

Section: Introductionmentioning

confidence: 99%

Prospective Evaluation of a Prenatal Sonographic Clubfoot Classification System

et al. 2013

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Background: The purpose of this study was to prospectively evaluate our recently described fetal sonographic classification system for prenatal diagnosis of clubfoot. Methods: Over 18 months, we prospectively enrolled consecutive pregnant patients evaluated for a prenatally diagnosed clubfoot. Prenatal sonographic scores assigned by a radiologist were compared to final clinical diagnosis and severity given by a pediatric orthopedic surgeon. Pearson's χ² test and logistic regression were used in statistical analyses on the subject level. Generalized estimating equations were used in analyses on the foot level to account for intrasubject correlation. Results: There were 50 subjects, with 26 unilateral and 24 bilateral clubfeet, according to the prenatal ultrasound (US). A total of 51 (69%) of 74 feet and 36 (72%) of 50 subjects had a postnatal diagnosis of clubfoot. The accuracy of diagnosis in cases of a severe, moderate, and mild US score was 94, 70, and 25%, respectively (p = 0.003 comparing moderate-severe vs. mild). US severity correlated with the Dimeglio classification scoring system (Spearman's correlation 0.30). Conclusion: The fetal sonographic scoring system is predictive of clinical severity after birth, and improves the ability to counsel families with a prenatal diagnosis of clubfoot.

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Outcome of Fetuses With Clubfeet Diagnosed by Prenatal Sonography

Cited by 47 publications

References 8 publications

Prenatal Diagnosis of Clubfoot: A Review of Current Available Methodology

Prenatal Diagnosis of Clubfoot: A Review of Current Available Methodology

Pé torto congênito

Prospective Evaluation of a Prenatal Sonographic Clubfoot Classification System

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