Outcome of food intake and nutritional status after discontinuation of a cow’s-milk-free diet post negative oral food challenge in infants and children

Abstract

Objective: To evaluate the outcome of food intake and nutritional status post discontinuation of a cow’s-milk-free diet after a negative oral food challenge.Methods: This was a prospective, uncontrolled study that evaluated food intake and nutritional status of a cohort of 80 infants and children under 5 years of age. Food intake and nutritional status were evaluated on the day of the oral food challenge test and after 30 days. Weight and height were measured on the day of the test and after 30 days.Results: The mean age of the patients was 18.7 ± 12.4 months, and 58.7% were male. After discontinuation of the elimination diet, the children showed daily intake increases in (P < 0.001), protein (P < 0.001), carbohydrates (P = 0.042), calcium from foods (P < 0.001), calcium from foods and supplements (P < 0.001), phosphorus (P < 0.001), and vitamin D from foods (P = 0.006). The Z-scores (n = 76) on the day of the oral food challenge test and 30 days after restarting the consumption of cow’s milk were as follows: weight-for-age (P < 0.001) and height-for-age (P < 0.001), respectively.Conclusion: Cow’s milk protein in the diet was associated with increased intake of energy, proteins, carbohydrates, calcium, phosphorus, and vitamin D, in addition to an increase in the Z-scores for weight-for-age and height-for-age.

Real-life data on the effectiveness of extensively hydrolyzed protein-based formula and amino acid–based formula in regaining weight and height in infants on a cow’s milk protein elimination diet

“…Although the EHF and AAF meet the requirements required by the Codex Alimentarius, there is evidence of lower growth during the cow's milk protein elimination diet, 23 as well as higher growth when the diet is restarted without restriction. 18,19 In this study, the EHF group received a cow's milk protein elimination diet for a mean period of 9.5 months, while in the AAF group, the mean time on the elimination diet was 8.7 months. It is important to highlight that half of the number of infants (50.0%) fed with AAF previously received EHF as a first option.…”

“…14 On the other hand, patients with CMPA may have an impaired nutritional status as well as reduced growth when compared to healthy children. 7,15,18,19,[21][22][23][24] Thus, it is extremely important to provide periodic assistance to children with CMPA, by trained professionals, such that the correct indication of the formula is carried out, according to the needs of each child, as well as adequate dietary guidelines regarding the requirements for nutrient supplementation, in order to avoid nutritional deficiencies. 1,3,[4][5][6] It is important to highlight that nutritional catch-up can provide an equalization to the growth observed in healthy children; however, accelerated nutritional recovery can contribute to the development of chronic noncommunicable diseases in adult life.…”

The Impact of Processing and Extraction Methods on the Allergenicity of Targeted Protein Quantification as Well as Bioactive Peptides Derived from Egg

“…The term “food allergy” refers to symptoms and conditions brought on by immunological reactions to food allergens in people already predisposed to having them. IgE antibody production is the most typical immunological response indicative of a food allergy [ 223 , 224 ]. Since an adverse immunological reaction to egg proteins causes atopic dermatitis and eosinophilic esophagitis, it follows that egg allergy is an IgE antibody-mediated allergy [ 225 , 226 ].…”

“…Since an adverse immunological reaction to egg proteins causes atopic dermatitis and eosinophilic esophagitis, it follows that egg allergy is an IgE antibody-mediated allergy [ 225 , 226 ]. Egg proteins’ ability to provoke an immune response is reflected in their stability in the face of heat and enzymatic digestion [ 206 , 207 , 208 , 209 , 210 , 211 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 220 , 221 , 222 , 223 , 224 , 225 , 226 , 227 ]. While both egg components contain proteins that can trigger an allergic reaction, the allergenic potential of EW proteins is greater than that of EY proteins.…”

Ingestão alimentar e estado nutricional de crianças com dieta de exclusão de leite de vaca: Um estudo de revisão

“…No levantamento inicial sobre ingestão alimentar e estado nutricional de crianças em dieta de exclusão de leite de vaca e derivados, foram identificados 441 artigos. Após a aplicação dos critérios de exclusão, foram selecionados para leitura 22 artigos, dos quais 18 foram incluídos no estudo (16,(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36). A Figura 1 apresenta o fluxograma para seleção dos artigos do estudo.…”