Background Catheter ablation (CA) has become a conventional treatment for atrial fibrillation (AF), but remains with high recurrence rate. The aim of this metaanalysis was to determine left atrial (LA) structure and function indices that predict recurrence of AF. Methods We systematically searched PubMed-Medline, EMBASE, Scopus, Google Scholar and the Cochrane Central Registry, up to September 2017 in order to select clinical trials and observational studies which reported echocardiographic predictors of AF recurrence after CA. Eighty-five articles with a total of 16 126 patients were finally included. Results The pooled analysis showed that after a follow-up period of 21 AE 12 months, patients with AF recurrence had larger LA diameter with weighted mean difference (WMD: 2Á99 ([95% CI 2Á50-3Á47], P<0Á001), larger LA volume index (LAVI) maximal and LAVI minimal (P<0Á0001 for both), larger LA area (P<0Á0001), lower LA strain (P<0Á0001) and lower LA total emptying fraction (LA EF) (P<0Á0001) compared with those without AF recurrence. The most powerful LA predictors (in accuracy order) of AF recurrence were as follows: LA strain <19% (OR: 3Á1[95% CI, -1.3-10Á4], P<0Á0001), followed by LA diameter ≥50 mm (OR: 2Á75, [95% CI 1Á66-4Á56,] P<0Á0001), and LAVmax >150 ml (OR: 2Á25, [95% CI, 1.1-5Á6], P = 0Á0002). Conclusions Based on this meta-analysis results, a dilated left atrium with diameter more than 50 mm and volume above 150 ml or myocardial strain below 19% reflect an unstable LA that is unlikely to hold sinus rhythm after catheter ablation for atrial fibrillation.