Outcome of recurrent cervical carcinoma following definitive irradiation

Reirradiation Using High-Dose-Rate Interstitial Brachytherapy for Locally Recurrent Cervical Cancer: A Single Institutional Experience

“…Previous studies have shown that if left untreated, the prognosis of patients who develop recurrent cervical cancer in a previously irradiated field is dismal; that is, the 5-year survival rate was only 1%. 17 Recent reports have suggested that although reirradiation using HDR-ISBT is associated with potential complications, it can result in durable disease control in appropriately selected patients. 5Y8 In the current study, reirradiation using HDR-ISBT achieved an overall response rate of 76.9%.…”

Image-Guided Stereotactic Body Radiation Therapy in Patients With Isolated Para-Aortic Lymph Node Metastases From Uterine Cervical and Corpus Cancer

“…Grigsby et al (8) reported that all patients with PALN metastasis died within 2 years after recurrence, despite the use of salvage radiation therapy (RT). This is due to the limited effectiveness of salvage therapies (9). Salvage surgery and RT have limited roles in patients with isolated PALN metastasis because their associated morbidity and mortality rates are high.…”

Outcomes in 24 selected patients with stage IVB cervical cancer and excellent performance status treated with radiotherapy and chemotherapy

“…8 During that period, the treatment options included re-irradiation, surgery, hyperthermia, and chemotherapy. Few patients received multimodality treatments.…”