Outcome of simultaneous thulium laser enucleation of bladder tumor and prostate in patients with non-muscle invasive bladder tumor and benign prostatic hyperplasia: a matched-pair comparison with a long-term follow-up

Wang, Yubin; Zhang, Zhiling; Shao, Jinkai; Lu, Yongan; Li, Rongshan

doi:10.1007/s00345-020-03158-3

Cited by 4 publications

(11 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The risk difference of BN/PU recurrence and progression was neither clinically meaningful nor statistically significant between treatment (TURBT + TURP) and control groups (TURBT alone). Our present findings are consistent with those of the meta‐analysis performed by Zhou et al [20] in terms of tumour recurrence and progression; however, our present meta‐analysis included recently published studies [16].…”

Section: Discussionsupporting

confidence: 93%

“…After applying the inclusion and exclusion criteria, 12 studies remained for systematic review. Table 1 lists the characteristics of these 12 studies [3–5,9–17]. We excluded the Tsivian et al [4] study due to the lack of a control group.…”

Section: Resultsmentioning

confidence: 99%

“…solitary or multifocal) and the grade and stage of the tumour. Six studies in this review reported a mean time to recurrence (the first recurrence), which is highlighted in Table 3 [9–12,16].…”

Section: Resultsmentioning

confidence: 99%

“…Although most urological surgeons may avoid concomitant single immediate intravesical chemotherapy (SIIC) at TURBT and TURP to avoid extravasation‐related side‐effects of intravesical chemotherapy, two studies (one retrospective and one RCT) reported the use of SIIC after a simultaneous endoscopic surgery for bladder tumour and BPH [10,16]. Both Li et al [10] and Wang et al [16] used laser technology to resect the bladder tumour and enucleation of the prostate adenoma, while SIIC was administered for all patients after surgery. They did not report any adverse events related to extravasation of the chemotherapeutic agents.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

The recurrence and progression risk after simultaneous endoscopic surgery of urothelial bladder tumour and benign prostatic hyperplasia: a systematic review and meta‐analysis

et al. 2020

View full text Add to dashboard Cite

Objectives To evaluate recurrence and progression risk after simultaneous endoscopic surgery of bladder cancer and benign prostatic hyperplasia (BPH), as simultaneous surgery is not an unusual scenario and theoretically simultaneous transurethral resection of bladder tumour (TURBT) and transurethral resection of the prostate (TURP) can lead to an increased risk of recurrence in the bladder neck and prostatic urethra (BN/PU). Methods We conducted a systematic review and meta‐analysis to assess the risk of recurrence (i.e. whole bladder and/or BN/PU) and tumour progression as outcomes after a simultaneous endoscopic surgery of bladder tumour and BPH, as compared to TURBT alone. We queried PubMed and Web of Science database on 1 January 2020. We used random‐ and/or fixed‐effects meta‐analytic models in the presence or absence of heterogeneity according to the I2 statistic, respectively. Results Nine retrospective and three clinical trial studies were selected after considering inclusion and exclusion criteria. We conducted the meta‐analysis on retrospective and randomised controlled trials (RCTs) separately. Eight retrospective and three RCT studies were included to assess the BN/PU recurrence risk and the summarised risk ratio (RR) was 1.02 (95% confidence interval [CI] 0.74–1.41) and 0.93 (95% CI 0.47–1.84), respectively. Five retrospective and two RCT studies were included to assess the progression risk and the summarised RR was 0.91 (95% CI 0.56–1.48) and 1.16 (95% CI 0.30–4.51), respectively. Eight retrospective and three RCT studies were included to assess the whole bladder recurrence risk and the summarised RR was 0.87 (95% CI 0.78–0.97) and 0.89 (95% CI 0.65–1.21), respectively. Conclusion We did not observe any increased risk of total bladder recurrence, BN/PU recurrence, or progression after a simultaneous endoscopic surgery of bladder tumour and BPH, as compared to TURBT alone.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The recurrence and progression risk after simultaneous endoscopic surgery of urothelial bladder tumour and benign prostatic hyperplasia: a systematic review and meta‐analysis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…After title and abstract screening, 29 articles underwent full-text evaluation. Ultimately, 15 studies with 2421 participants were included in the qualitative and quantitative synthesis (3 RCTs and 12 retrospective observational studies) [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. The PRISMA flow chart of the study-selection process is illustrated in Figure 1 , and all excluded studies, along with reasons for exclusion, are presented in Supplementary Material S3 .…”

Section: Resultsmentioning

confidence: 99%

Concomitant Endoscopic Surgery for Bladder Tumors and Prostatic Obstruction: Are We Safely Hitting Two Birds with One Stone? A Systematic Review and Meta-Analysis

Savvides

Pyrgidis

Langas

et al. 2022

JCM

View full text Add to dashboard Cite

Background: Lower urinary tract symptoms (LUTS) caused by benign prostatic obstruction (BPO) and bladder tumors may co-exist, especially among elderly patients. Transurethral resection of bladder tumors (TURBT) and endoscopic surgery for benign prostatic obstruction in the same setting are avoided by many surgeons due to concerns for tumor cell seeding and recurrences in the prostatic urethra. Aim: The aim of this study was assess the effect of concomitant TURBT and endoscopic BPO surgery on oncological safety and patient quality of life via systematic review and meta-analysis. Methods: We searched the PubMed, Cochrane Library, EMBASE, Scopus, and Clinicaltrials.gov databases and sources of grey literature published before June 2021 for relevant studies. We performed a random-effects meta-analysis of odds ratios (ORs) or weighted mean differences (WMD) to compare concomitant TURBT and BPO surgery versus TURBT alone in terms of recurrence and progression rates. Accordingly, we undertook multiple subgroups and sensitivity analyses (PROSPERO: CRD42020173363). Results: Three randomized and twelve retrospective observational studies with 2421 participants were included. Across studies with good methodological quality, no statistically significant differences were demonstrated regarding overall bladder tumors recurrence rates between concomitant endoscopic BPO surgery and TURBT versus TURBT alone (OR: 0.81, 95% CI: 0.60–1.09, I2 = 42%). Similarly, no significant differences were observed in recurrences located at the bladder neck and/or prostatic urethra (OR: 1.06, 95% CI: 0.76–1.47, I2 = 0%), time to first recurrence (WMD: −0.2 months, 95% Cl: −2.2–1.8, I2 = 48%), and progression rate (OR: 1.05, 95% CI: 0.67–1.64, I2 = 0%). Subgroup analyses based on tumor grade, number of tumors, and utilization of single-instillation chemotherapy post-TURBT did not detect any significant differences in overall bladder tumor recurrence. The level of evidence was estimated as low for all outcomes. Concomitant surgery improved lower urinary tract symptoms. Conclusion: Concomitant endoscopic BPO surgery and TURBT are oncologically safe and improve LUTS-related quality of life.

show abstract

Photoactivatable metal organic framework for synergistic ferroptosis and photodynamic therapy using 450 nm laser

Chen

Gu²,

Ma³

et al. 2023

Chemical Engineering Journal

View full text Add to dashboard Cite

Outcome of simultaneous thulium laser enucleation of bladder tumor and prostate in patients with non-muscle invasive bladder tumor and benign prostatic hyperplasia: a matched-pair comparison with a long-term follow-up

Cited by 4 publications

References 28 publications

The recurrence and progression risk after simultaneous endoscopic surgery of urothelial bladder tumour and benign prostatic hyperplasia: a systematic review and meta‐analysis

The recurrence and progression risk after simultaneous endoscopic surgery of urothelial bladder tumour and benign prostatic hyperplasia: a systematic review and meta‐analysis

Concomitant Endoscopic Surgery for Bladder Tumors and Prostatic Obstruction: Are We Safely Hitting Two Birds with One Stone? A Systematic Review and Meta-Analysis

Photoactivatable metal organic framework for synergistic ferroptosis and photodynamic therapy using 450 nm laser

Contact Info

Product

Resources

About