Outcome one year after robot-assisted rectal cancer surgery: a consecutive cohort study

Harsløf, Sanne; Stouge, Anders; Thomassen, Niels; Ravn, Sissel; Laurberg, Søren; Iversen, Lene Hjerrild

doi:10.1007/s00384-017-2880-y

Cited by 9 publications

(10 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although representing the implementation phase, the incidence of major LARS seems to be comparable with previous studies 29,30 . A potential explanation could be the learning curve.…”

Section: Discussionsupporting

confidence: 76%

“…The urinary dysfunction was then categorised into mild (0-7), moderate (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19), or severe (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35). 17 The sexual function in female was assessed using the Female Sexual Function Index (FSFI) questionnaire, consisting of 18 questions, leading to a total score with higher scores indicating better function on a scale of 2-36.…”

Section: Endpointsmentioning

confidence: 99%

“…Although representing the implementation phase, the incidence of major LARS seems to be comparable with previous studies. 29,30 A potential explanation could be the learning curve. Incidence of major LARS was comparable to 53% at 12 months after robotic surgery described by Harslof et al 29 Similar results were seen for urogenital function as well.…”

Section: Functional Outcomementioning

confidence: 99%

“…29,30 A potential explanation could be the learning curve. Incidence of major LARS was comparable to 53% at 12 months after robotic surgery described by Harslof et al 29 Similar results were seen for urogenital function as well. IPSS score was comparable to several previous studies.…”

Section: Functional Outcomementioning

confidence: 99%

See 3 more Smart Citations

Implementation of robot‐assisted total mesorectal excision by multiple surgeons in a large teaching hospital: Morbidity, long‐term oncological and functional outcome

Hol

Doğan

Blanken-Peeters

et al. 2021

Robotics Computer Surgery

View full text Add to dashboard Cite

Background Robot‐assisted total mesorectal excision (TME) might offer benefits in less morbidity, better functional and long‐term outcome over laparoscopic TME. Methods All consecutive patients undergoing robot‐assisted TME for rectal cancer during implementation between May 2015 and December 2019 performed by five surgeons in a single centre were included. Outcomes included local recurrence rate at 3 years, conversion rate, circumferential resection margin (CRM) positivity rate, 30‐day postoperative morbidity and outcomes of low anterior resection syndrome (LARS) questionnaires. Results In 105 robot‐assisted TME, local recurrence rate at 3 years was 7.4%, conversion to open surgery rate was 8.6%, CRM positivity rate was 5.7%, 73.3% had good quality specimen, postoperative morbidity rate was 47.6% and anastomotic leakage rate was 9.0%. Incidence of major LARS was 55.3%. Conclusions results of this study described acceptable morbidity, functional and long‐term outcome during implementation of robotic TME for rectal cancer by multiple surgeons in a single centre.

show abstract

“…Although representing the implementation phase, the incidence of major LARS seems to be comparable with previous studies 29,30 . A potential explanation could be the learning curve.…”

Section: Discussionsupporting

confidence: 76%

Section: Endpointsmentioning

confidence: 99%

Section: Functional Outcomementioning

confidence: 99%

Section: Functional Outcomementioning

confidence: 99%

See 2 more Smart Citations

Implementation of robot‐assisted total mesorectal excision by multiple surgeons in a large teaching hospital: Morbidity, long‐term oncological and functional outcome

Hol

Doğan

Blanken-Peeters

et al. 2021

Robotics Computer Surgery

View full text Add to dashboard Cite

show abstract

“…Introduction of minimally invasive techniques (either laparoscopic or robotic) to rectal cancer surgery improved short-term clinical outcomes, including reduced length of stay (LOS), surgical site infection rate and postoperative pain, while maintaining similar oncological outcomes [6–9]. Although this approach facilitates better visualization of the operative field, especially regarding pelvic nerves, no improvement in terms of LARS has been noted so far [10].…”

Section: Introductionmentioning

confidence: 99%

Functional outcomes after resections for low rectal tumors: comparison of Transanal with laparoscopic Total Mesorectal excision

et al. 2019

View full text Add to dashboard Cite

Background Aim of this study was to evaluate functional outcomes of transanal total mesorectal excision (TaTME) in comparison to conventional laparoscopic approach (LaTME) in terms of low anterior resection syndrome (LARS). Methods Forty-six patients who underwent total mesorectal excision for low rectal cancer between 2013 and 2017 were enrolled. Primary outcome was the severity of faecal incontinence, assessed both before the treatment and 6 months after ileostomy reversal. LARS score and Jorge-Wexner scale were utilized to analyze its severity. Results Twenty (87%) from TaTME and 21 (91%) from LaTME group developed LARS postoperatively. There were no significant differences between groups in terms of LARS occurrence ( p = 0.63) and severity. The median Wexner score was comparable in both groups (8 [IQR: 4–12] vs 7 [3–11], p = 0.83). Univariate analysis revealed that postoperative complications were a risk factor for LARS development ( p = 0.02). Perioperative outcomes, including operative time, blood loss and intraoperative adverse events did not differ significantly between groups either. Five TaTME patients developed postoperative complications, while there were morbidity 6 cases in LaTME group. Quality of mesorectal excision was comparable with 20 and 19 complete cases in TaTME and LaTME groups, respectively. Conclusions TaTME provided comparable outcomes in terms of functional outcomes in comparison to LaTME for total mesorectal excision in low rectal cancers. Having said that, LARS prevalence is still high and requires further evaluation of the technique.

show abstract

Low anterior resection syndrome

Ryoo

2023

Annals of Gastroent Surgery

View full text Add to dashboard Cite

Low anterior resection syndrome (LARS) is the distressful defecatory functional problem after sphincter‐saving surgery for rectal cancer. Although the symptoms of fecal urgency, frequency, and incontinence may develop in most of the patients after surgery, there is no definitive treatments for LARS. Multifactorial etiologies and various risk factors have been identified, but the reduction of storage capacity in the rectum is one of the main reasons for LARS. Anal sphincter muscle or nerve damage during rectoanal resection or anastomosis construction, and intersphincteric resection for low‐lying tumors or hand‐sewing anastomosis, are the absolute risk factors for LARS. Preoperative radiotherapy, postoperative complications, such as anastomosis leakage, or longer duration of stoma, are also risk factors. The severity of LARS can be confirmed using the LARS score questionnaire. The questionnaire has been translated to numerous language versions including Korean and have been validated. Diverse empirical treatments, such as loperamide, fiber, probiotics, or enema, have been tried, but the safety and efficacy have not been verified yet. The 5‐Hydroxytryptamine (5‐HT) receptor antagonist, ramosetron, used for diarrhea‐dominant irritable bowel syndrome, is one potential drug for relieving the symptoms of major LARS. A randomized‐controlled trial suggested the use of ramosetron could be safe and efficacious for patients who have major LARS after sphincter‐saving rectal cancer surgery. Novel techniques or drugs for relieving the symptoms of LARS should be developed more and further studies are necessary.

show abstract

Outcome one year after robot-assisted rectal cancer surgery: a consecutive cohort study

Cited by 9 publications

References 25 publications

Implementation of robot‐assisted total mesorectal excision by multiple surgeons in a large teaching hospital: Morbidity, long‐term oncological and functional outcome

Implementation of robot‐assisted total mesorectal excision by multiple surgeons in a large teaching hospital: Morbidity, long‐term oncological and functional outcome

Functional outcomes after resections for low rectal tumors: comparison of Transanal with laparoscopic Total Mesorectal excision

Low anterior resection syndrome

Contact Info

Product

Resources

About