Outcomes after completion thyroidectomy versus total thyroidectomy for differentiated thyroid cancer: A single‐center experience

Dedhia, Priya H.; Stoeckl, Elizabeth; McDow, Alexandria D.; Pitt, Susan C.; Sippel, Rebecca S.; Long, Kristin L.

doi:10.1002/jso.26044

Cited by 15 publications

(17 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…44,45 Similar to up-front total thyroidectomy, adequate completion thyroidectomy is optimized by referral to a highvolume thyroid surgeon. 46,47 Another potential advantage of hemithyroidectomy is the possibility to remain euthyroid postoperatively. The 2015 ATA guidelines recommend maintaining TSH between 0.5 and 2 mIU/L after hemithyroidectomy for low-risk DTCs.…”

Section: Extent Of Surgerymentioning

confidence: 99%

See 1 more Smart Citation

Thyroid cancer, recent advances in diagnosis and therapy

Nabhan

Dedhia

Ringel

2021

Intl Journal of Cancer

Self Cite

100

View full text Add to dashboard Cite

Over the past several decades, the approach to the diagnosis and management of patients with follicular cell-derived thyroid cancer has evolved based on improved classification of patients better matching clinical outcomes, as well as advances in imaging, laboratory, molecular technologies and knowledge. While thyroid surgery, radioactive iodine therapy and TSH suppression remain the mainstays of treatment, this expansion of knowledge has enabled de-escalation of therapy for individuals diagnosed with low-risk well-differentiated thyroid cancer; better definition of treatment choices for patients with more aggressive disease; and improved ability to optimize treatments for patients with persistent and/or progressive disease. Most recently, the advancement of knowledge regarding the molecular aspects of thyroid cancer has improved thyroid cancer diagnosis and has enabled individualized therapeutic options for selected patients with the most aggressive forms of the disease.Guidelines from multiple societies across the world reflect these changes, which focus on taking a more individualized approach to clinical management. In this review, we discuss the current more personalized approach to patients with follicular cell-derived thyroid cancer and point toward areas of future research still needed in the field.

show abstract

Section: Extent Of Surgerymentioning

confidence: 99%

“…Finally, recurrent laryngeal nerve injury and voice and swallowing dysfunction are less common after hemithyroidectomy 44,45 . Similar to up‐front total thyroidectomy, adequate completion thyroidectomy is optimized by referral to a high‐volume thyroid surgeon 46,47 …”

Section: Thyroid Cancer Diagnosis Initial Management and Stagingmentioning

confidence: 99%

Thyroid cancer, recent advances in diagnosis and therapy

Nabhan

Dedhia

Ringel

2021

Intl Journal of Cancer

Self Cite

100

View full text Add to dashboard Cite

show abstract

“…Historically, total thyroidectomy as the initial procedure was considered to be safer than lobectomy, followed by completion thyroidectomy in terms of postoperative complications and in terms of completeness of resection of the thyroid tissue [31]. Today, however, it has been shown in many retrospective studies that completion thyroidectomy does not carry more morbidity than initial upfront total thyroidectomy and that the completeness of resection, as measured by postoperative serum Tg, is comparable as well [32][33][34][35]. In fact, several studies have even demonstrated that the rate of temporary postoperative hypoparathyroidism may be lower for completion thyroidectomy [34,35].…”

Section: Oncologic Considerations: Completion Thyroidectomy and Survivalmentioning

confidence: 99%

“…Today, however, it has been shown in many retrospective studies that completion thyroidectomy does not carry more morbidity than initial upfront total thyroidectomy and that the completeness of resection, as measured by postoperative serum Tg, is comparable as well [32][33][34][35]. In fact, several studies have even demonstrated that the rate of temporary postoperative hypoparathyroidism may be lower for completion thyroidectomy [34,35]. The question of the safety of completion lobectomy is, therefore, today, no longer an issue.…”

Section: Oncologic Considerations: Completion Thyroidectomy and Survivalmentioning

confidence: 99%

Thyroid Lobectomy for Low to Intermediate Risk Differentiated Thyroid Cancer

Hartl

Guerlain

Breuskin

et al. 2020

Cancers

View full text Add to dashboard Cite

Many recent publications and guidelines have promoted a “more is less” approach in terms of treatment for low to intermediate risk differentiated thyroid cancer (DTC), which comprise the vast majority of thyroid cancers: less extensive surgery, less radioactive iodine, less or no thyroid hormone suppression, and less frequent or stringent follow-up. Following this approach, thyroid lobectomy has been proposed as a means of decreasing short- and long-term postoperative morbidity while maintaining an excellent prognosis for tumors meeting specific macroscopic and microscopic criteria. This article will examine the pros and cons of thyroid lobectomy for low to intermediate risk cancers and discuss, in detail, criteria for patient selection and oncological outcomes.

show abstract

“…There is still controversy as to whether patients undergoing a completion thyroidectomy for this reason have a comparable, increased or decreased risk of complications compared to those submitted to primary thyroid surgery [16][17][18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Risk of Complications in Patients Undergoing Completion Thyroidectomy after Hemithyroidectomy for Thyroid Nodule with Indeterminate Cytology: An Italian Multicentre Retrospective Study

Canu

Medas

Cappellacci

et al. 2022

Cancers

View full text Add to dashboard Cite

There is still controversy as to whether patients undergoing a completion thyroidectomy after a hemithyroidectomy for a thyroid nodule with an indeterminate cytology have a comparable, increased or decreased risk of complications compared to those submitted to primary thyroid surgery. The main aim of this study was to investigate this topic. Patients undergoing a thyroidectomy for thyroid nodular disease with an indeterminate cytology in four high-volume thyroid surgery centres in Italy, between January 2017 and December 2020, were retrospectively analysed. Based on the surgical procedure performed, four groups were identified: the TT Group (total thyroidectomy), HT Group (hemithyroidectomy), CT Group (completion thyroidectomy) and HT + CT Group (hemithyroidectomy with subsequent completion thyroidectomy). A total of 751 patients were included. As for the initial surgery, 506 (67.38%) patients underwent a total thyroidectomy and 245 (32.62%) a hemithyroidectomy. Among all patients submitted to a hemithyroidectomy, 66 (26.94%) were subsequently submitted to a completion thyroidectomy. No statistically significant difference was found in terms of complications comparing both the TT Group with the HT + CT Group and the HT Group with the CT Group. The risk of complications in patients undergoing a completion thyroidectomy after a hemithyroidectomy for a thyroid nodule with an indeterminate cytology was comparable to that of patients submitted to primary thyroid surgery (both a total thyroidectomy and hemithyroidectomy).

show abstract

Outcomes after completion thyroidectomy versus total thyroidectomy for differentiated thyroid cancer: A single‐center experience

Cited by 15 publications

References 17 publications

Thyroid cancer, recent advances in diagnosis and therapy

Thyroid cancer, recent advances in diagnosis and therapy

Thyroid Lobectomy for Low to Intermediate Risk Differentiated Thyroid Cancer

Risk of Complications in Patients Undergoing Completion Thyroidectomy after Hemithyroidectomy for Thyroid Nodule with Indeterminate Cytology: An Italian Multicentre Retrospective Study

Contact Info

Product

Resources

About