Outcomes after multi-modality treatment of musculoskeletal tumours

Marsden, F. W.; Swanson, Cheryl

doi:10.1080/17453674.1997.11744711

Cited by 12 publications

(6 citation statements)

References 14 publications

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“…In half of the long‐term osteosarcoma survivor studies that we reviewed for this study, the authors reported on functional 21, 22 or psychosocial 6, 18, 23–26 outcomes. Of the remaining outcome studies reviewed, in which investigators assessed both functional and psychosocial outcomes 5, 17, 27–32, only one study compared a psychosocial variable with physical function.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial and functional outcomes in long‐term survivors of osteosarcoma: A comparison of limb‐salvage surgery and amputation

Robert

Ottaviani

Huh

et al. 2010

Pediatric Blood & Cancer

117

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BackgroundTraditionally, physicians have believed that limb‐salvage surgery has functional and cosmetic advantages over amputation, yet the literature is equivocal. Therefore, we sought to compare the psychosocial and functional outcomes in osteosarcoma survivors after limb‐salvage surgery and amputation. We hypothesized there to be neither psychosocial nor functional outcome differences between groups.ProcedureParticipants received treatment of extremity osteosarcoma, had received their cancer diagnosis at least 2 years prior, and were at least 16 years old. A comprehensive set of validated psychosocial and functional measures was used to assess outcome.ResultsFifty‐seven patients participated in this study (33 who underwent limb‐salvage surgery and 24 who underwent amputation). Participants had gone 12–24 years since diagnosis and were 16–52 years old at study participation. We used multiple linear regression models to examine differences in quality of life, body image, self‐esteem, and social support between the two groups and found no differences. Lower limb function was a significant predictor of quality of life (P < 0.001), whereas surgery type did not impact this relationship. Body image was rated significantly worse by those who underwent late amputation, amputation after failed limb salvage, than by those who did not.ConclusionsParticipants with more functional lower limbs had better quality of life than did those with less functional lower limbs regardless of whether they underwent amputation or limb‐salvage surgery. Pediatr Blood Cancer 2010;54:990–999 © 2010 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Psychosocial and functional outcomes in long‐term survivors of osteosarcoma: A comparison of limb‐salvage surgery and amputation

Robert

Ottaviani

Huh

et al. 2010

Pediatric Blood & Cancer

117

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“…Investigations on smaller numbers of patients from elsewhere in the United States,45 from Australia,46 and from the Netherlands47 reveal no significant differences in psychological outcomes and HRQoL between amputees and those who have undergone limb salvage. There are 2 additional perspectives that are worthy of consideration in evaluating such information: patients who proceed to amputation are seldom candidates for limb‐sparing surgery,46 and patients who have amputations for cancer may fare much better than traumatic amputees in terms of adaptation to disability 48. In this latter regard, a study of >500 patients who had experienced leg‐threatening injuries, from a consortium of 8 level 1 trauma centers in the United States, revealed that the HRQoL was no different in those who had reconstructive (limb‐salvage) surgery and those who had amputations 49.…”

Section: The Challengementioning

confidence: 95%

Bone and soft tissue sarcomas are often curable—But at what cost?

Barr¹,

Wunder²

2009

Cancer

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“…Improved function and quality of life have been attributed to limb salvage but have not been universally demonstrated in the adult population [33]. A number of studies document better physical function in patients with limb salvage compared to patients with amputation [1,10,15,22,24,32,38,39]. Other studies have reported no difference in function with limb salvage [4,21,23], but a higher quality of life with limb salvage [37].…”

Section: Introductionmentioning

confidence: 99%

“…Investigation performed at Moffitt Cancer Center and All Children's Hospital (St Petersburg, FL). quality of life with limb salvage has been reported due to less social alienation and increased self-esteem compared to amputations [20,24,30]. In contrast, some authors report equivalent quality of life in limb salvage and amputation patients [22,23,26,34,36].…”

Section: Introductionmentioning

confidence: 99%

What is the Emotional Acceptance After Limb Salvage with an Expandable Prosthesis?

Henderson¹,

Pepper

Marulanda

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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Background Limb preservation surgery for extremity sarcomas offers the promise of improved function and cosmesis over amputation. Application of limb salvage surgery for pediatric patients with expandable metallic endoprostheses is gaining acceptance. The few studies reporting these devices have focused on functional outcomes; one has addressed quality of life. Questions/purposes We asked the following questions: (1) how happy are these patients; (2) how do these patients perceive their bodies; (3) do these children have difficulty with social interactions; and (4) how satisfied are patients and their parents with their outcomes?

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Outcomes after multi-modality treatment of musculoskeletal tumours

Cited by 12 publications

References 14 publications

Psychosocial and functional outcomes in long‐term survivors of osteosarcoma: A comparison of limb‐salvage surgery and amputation

Psychosocial and functional outcomes in long‐term survivors of osteosarcoma: A comparison of limb‐salvage surgery and amputation

Bone and soft tissue sarcomas are often curable—But at what cost?

What is the Emotional Acceptance After Limb Salvage with an Expandable Prosthesis?

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