Outcomes after primary percutaneous coronary intervention in octogenarians and nonagenarians with ST‐segment elevation myocardial infarction: From the Western Denmark heart registry

Antonsen, Lisbeth; Jensen, Lisette Okkels; Terkelsen, Christian Juhl; Tilsted, Hans‐Henrik; Junker, Anders; Mæng, Michael; Hansen, Knud Noerregaard; Lassen, Jens Flensted; Thuesen, Leif; Thayssen, Per

doi:10.1002/ccd.24591

Cited by 72 publications

(66 citation statements)

References 35 publications

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“…In-hospital mortality was low (19%), but was significantly higher in patients with shock. A recent Danish study that included 109 nonagenarians undergoing PCI after STEMI showed a 30-day mortality of 25.8%, a 1-year mortality of 32.5%, and a 5-year mortality of 57.3% [26]. Those three small registries suggested that selected nonagenarians with STEMI benefit from pPCI.…”

Section: Discussionmentioning

confidence: 97%

Outcomes of primary percutaneous coronary interventions in nonagenarians with acute myocardial infarction

Helft

Georges

Mouranche

et al. 2015

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 97%

Outcomes of primary percutaneous coronary interventions in nonagenarians with acute myocardial infarction

Helft

Georges

Mouranche

et al. 2015

International Journal of Cardiology

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“…Recently, the Western Denmark Heart Registry analysis of primary PCI in octogenarians and nonagenarians with STEMI showed that a total of 1,322 elderly patients were treated with primary PCI, which corresponds to 11.6% of the total STEMI population treated with primary PCI 9. In another study, performed in Turkey, Oduncu et al10 reported that 8.1% of the primary PCI population consisted of patients aged ≥80 years.…”

Section: Current Status Of Primary Pci In the Elderly With Stemimentioning

confidence: 99%

Percutaneous coronary intervention in the elderly with ST-segment elevation myocardial infarction

Gao¹,

Liu²,

Qin³

et al. 2014

CIA

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As a result of increased life expectancy, octogenarians constitute an increasing proportion of patients admitted to hospital for ST-segment elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention is currently the treatment of choice for octogenarians presenting with STEMI. The recent literature on this topic has yielded controversial results, even though advances in drug-eluting stents and new types of antithrombotic agents are improving the management of STEMI and postoperative care. In this paper, we review the current status of percutaneous coronary intervention in the elderly with STEMI, including the reasons for their high mortality and morbidity, predictors of mortality, and strategies to improve outcomes.

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“…PCI is being increasingly performed in elderly patients [8,9,10,11]. Reported peri-procedural mortality is 6.9-7.6% in elective procedures [9,12,13,14], but can be as high as 15.5-17.2% in octogenarians with acute ST elevated myocardial infarcts [15,16]. Patients' subjective perception of their HRQOL is equally as important as objective end-points such as mortality in considering PCI [4,17,18].…”

Section: Introductionmentioning

confidence: 99%

A Systematic Review on the Quality of Life Benefits after Percutaneous Coronary Intervention in the Elderly

Shan

Saxena²,

McMahon³

2014

Cardiology

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Aims: Percutaneous coronary intervention (PCI) is being increasingly performed on elderly patients with acceptable peri-procedural outcomes and long-term survival. We aim to systematically review the health-related quality of life (HRQOL) following PCI in the elderly which is an important measure of procedural success. Methods: A systematic review of clinical studies before September 2012 was performed to identify HRQOL in the elderly after PCI. Strict inclusion and exclusion criteria were applied. Quality appraisal of each study was also performed using pre-defined criteria. HRQOL results were synthesised through a narrative review with full tabulation of results of all included studies. Results: Elderly patients have significant improvements in cardiovascular well-being. Early HRQOL appears improved from baseline, but recovery in physical health may be slower than in younger patients. HRQOL is comparable to an age-matched general population and younger patients undergoing PCI. Conservative management is not able to offer the same HRQOL benefits. Coronary artery bypass graft surgery may be superior to PCI in the very elderly. Significant heterogeneity and bias exists. Lack of appropriate data precluded meta-analysis. Conclusion: HRQOL after PCI in the elderly can improve for at least 1 year across a broad range of health domains, and is comparable to an age-matched general population and younger patients undergoing PCI. Given a limited number of articles and patients included, more prospective studies are needed to better identify the benefits for elderly patients.

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Outcomes after primary percutaneous coronary intervention in octogenarians and nonagenarians with ST‐segment elevation myocardial infarction: From the Western Denmark heart registry

Cited by 72 publications

References 35 publications

Outcomes of primary percutaneous coronary interventions in nonagenarians with acute myocardial infarction

Outcomes of primary percutaneous coronary interventions in nonagenarians with acute myocardial infarction

Percutaneous coronary intervention in the elderly with ST-segment elevation myocardial infarction

A Systematic Review on the Quality of Life Benefits after Percutaneous Coronary Intervention in the Elderly

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