Outcomes and Complications of Sclerotherapy for Venous Malformations

Qiu, Yajing; Chen, Hui; Lin, Xiaoxi; Hu, Xiaojie; Jin, Yunbo; Ma, Gang

doi:10.1177/1538574413492390

Cited by 72 publications

(43 citation statements)

References 39 publications

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“…STS, polidocanol, and bleomycin were used less often, and showed proportionally less complications. Differences between these agents were, however, statistically insignificant [20]. The safety of detergent sclerosants thus warrants further investigations.…”

Section: Discussionmentioning

confidence: 99%

“…A recent review article on sclerotherapy reported that ethanol caused the most skin damage and nerve injuries, as well as serious systemic side-effects [20]. They also found that ethanolamine oleate was considered the most effective sclerosant but produced the highest rate of muscle and renal damage [20]. STS, polidocanol, and bleomycin were used less often, and showed proportionally less complications.…”

Section: Discussionmentioning

confidence: 99%

“…We treated only a few patients with ethanol or bleomycin, and so cannot draw definitive conclusions. A recent review article on sclerotherapy reported that ethanol caused the most skin damage and nerve injuries, as well as serious systemic side-effects [20]. They also found that ethanolamine oleate was considered the most effective sclerosant but produced the highest rate of muscle and renal damage [20].…”

Section: Discussionmentioning

confidence: 99%

“…Although sclerotherapy is minimally invasive and often safe [8,16], complications ranging from mild skin ulcerations to nerve injuries, tissue necrosis, gross hemoglobinuria, blood coagulation problems, pulmonary hypertension, and even lethal pulmonary embolism do occur [8,[17][18][19][20]. Because sclerosants and interventional techniques differ in safety and efficacy, identification of factors predisposing to complications is mandatory.…”

Section: Introductionmentioning

confidence: 99%

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Complications of sclerotherapy for 75 head and neck venous malformations

Castrén

Aronniemi

Klockars

et al. 2015

Eur Arch Otorhinolaryngol

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Sclerotherapy is one treatment option for head and neck venous malformations (VMs). Evaluation of complication risks is, however, essential to improve its safety. We aimed to systematically report sclerotherapy complications by means of the Clavien-Dindo classification and to distinguish factors predisposing to complications. We identified our institution's head and neck VM patients who received sclerotherapy between 1 January 2007 and 31 August 2013, analyzed patient reports retrospectively, and applied to them the Clavien-Dindo classification. Our 75 VM patients underwent a total of 150 sclerotherapy sessions. The most common sclerosants were 3 % sodium tetradecyl sulfate and polidocanol. Complications occurred in 13 patients (17.3 %) and in 15 sessions (10.0 %); 3 complications required extensive postprocedural treatment and caused permanent morbidity, whereas 12 received conservative treatment. Patients with sclerotherapy complications underwent more treatments (p = 0.009) and more often needed further surgery (p = 0.007). We thus consider sclerotherapy a relatively safe treatment modality for head and neck VMs. To avoid complications, evaluation of VM characteristics and optimal treatment technique in a multidisciplinary team is vital.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Complications of sclerotherapy for 75 head and neck venous malformations

Castrén

Aronniemi

Klockars

et al. 2015

Eur Arch Otorhinolaryngol

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“…[2][3][4] Polidocanol (POL) and sodium tetradecyl sulfate are the most common agents for sclerosing foam preparations, [5][6][7][8][9] which perform with better potency than liquids for venous anomalies. 10 Guided visible foam sclerotherapy for VMs with ultrasound or digital subtraction angiography (DSA) has become a research focus and academic front contributing to its accuracy and safety.…”

mentioning

confidence: 99%

A New Method for Using Radiopaque Sclerosing Foam to Treat Venous Malformations

Liu²,

Liu³

2015

Dermatologic Surgery

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Successful postoperative analgesia with ilio‐inguinal nerve block following sclerotherapy for a labial venous malformation

Kim

Josephs

Tsui

2020

Anaesthesia Reports

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Though ilio-inguinal nerve block has been commonly utilised in male urologic surgery, a single injection ilioinguinal nerve block alone has not previously been reported for analgesia of the vulva. In this report, we describe the case of a 14-year-old girl undergoing sclerotherapy of a venous malformation affecting the labia majora and minora. After induction of anaesthesia, we performed an ultrasound-guided ilio-inguinal nerve block using a total volume of 15 ml of ropivacaine 0.2% with 1 lg.ml À1 dexmedetomidine which provided effective postoperative analgesia. Though the patient received intravenous analgesia intra-operatively and had an inpatient bed reserved in anticipation of severe postoperative pain, she required no further analgesia and was discharged home following 2 hours in the postoperative anaesthesia care unit. With the additional use of dexmedetomidine resulting in prolonged efficacy of the block, the patient reported effective postoperative relief for approximately 30 hours, solely using ibuprofen for pain relief. This case reminds clinicians that the ilioinguinal nerve block may provide benefit not only for male urologic surgery but also for procedures involving the external female genitalia, with extended analgesia with the use of dexmedetomidine.

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Outcomes and Complications of Sclerotherapy for Venous Malformations

Abstract: Sclerotherapy is effective for VMs. However, there is limited evidence from randomized clinical trials to support the use of any kinds of sclerosants.

Cited by 72 publications

References 39 publications

Complications of sclerotherapy for 75 head and neck venous malformations

Complications of sclerotherapy for 75 head and neck venous malformations

A New Method for Using Radiopaque Sclerosing Foam to Treat Venous Malformations

Successful postoperative analgesia with ilio‐inguinal nerve block following sclerotherapy for a labial venous malformation

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