Outcomes and Readmission in Patients With Retinal Artery Occlusion (from the Nationwide Readmission Database)

Suri, K.; Majmundar, Monil; Kumar, Ashish; Patel, Kunal N; Zhou, Xioa Yi; Zala, Harshvardhan; Kalra, Ankur

doi:10.1016/j.amjcard.2022.07.040

Cited by 6 publications

(11 citation statements)

References 6 publications

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“…The assessments of mortality in patients with RAO have been undertaken in several studies [8,12,[15][16][17][18][19][20][21][22][23][24][25][26][27][28][29], some of which date back over forty years [8,16,17], and show that patients with RAO had a shortened life expectancy [8,16,17]. However, the study by De Potter et al concluded that although the survival rate of 151 RAO patients was lower than that of the age-and gender-matched control group, there was no statistically significant difference in the survival rate between RAO patients and control group (26% vs 21%; P = 0.29).…”

Section: Discussionmentioning

confidence: 99%

“…Most studies included patients with RAO [21,22,[26][27][28][29], some studies only included patients with central retinal artery occlusion (CRAO) [23,24]; the studies also differed in the duration of follow-up and the size of the groups evaluated, and only few studies included a control group [21][22][23][24][26][27][28][29]. In the study by Mir et al, in-hospital mortality in CRAO patients was 1.3% [24].…”

Section: Discussionmentioning

confidence: 99%

“…The results of previous studies show that the patients with RAO, so far, have only rarely been subjected to appropriate diagnostic management [13,14]. Data on the mortality of patients with RAO are modest, some studies were performed decades ago, not all of the available studies present consistent results, moreover there are few studies with a large study group, long follow-up period or a control group [8,12,[15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]. The aim of this study was to assess long-term mortality after RAO in the European population, and to identify risk factors for death in this group of patients.…”

Section: Introductionmentioning

confidence: 99%

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Long-term mortality after retinal artery occlusion – a single centre study

Roskal-Wałek¹,

Mackiewicz²,

Wałek³

et al. 2023

Ann Agric Environ Med.

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Introduction and Objective.Retinal artery occlusion (RAO) is an ophthalmic and systemic emergency requiring urgent diagnosis and treatment. Data regarding mortality in this group, especially in the European population, are modest. The aim of this study is to assess all-cause mortality in post-RAO patients. Materials and method. This is a retrospective, single-centre study involving 198 patients following RAO diagnosed in 2004-2020. The control group included 198 patients after cataract surgery matched for gender and age, with the date of cataract surgery corresponding to the date of the RAO. Results. The average follow-up of the study population was 6.32±2.15 years. Post-RAO patients had significantly higher risk of all-cause mortality (Log-rank test p = 0.001), also when stratified for ages below 75 years (Log-rank test p = 0.016) and those aged 75 and over (Log-rank test p = 0.001). In the group of patients without cardiovascular events before RAO/ cataract surgery, post-RAO patients were also at higher risk of all-cause mortality (Log-rank test p = 0.011), but when stratified according to age, those observations were borderline significant (Log-rank test p = 0.083 for a group of patients aged less than 75 years, and p = 0.051 for patients aged 75 and over). Cox analysis showed that in the group of post-RAO patients, the main risk factors for all-cause mortality were age (HR 1.07, 95%CI 1.04-1.1; p < 0.001), ischemic heart disease (HR 1.72; 95%CI 1.08-2.72; p = 0.022), and permanent atrial fibrillation (HR 2.18, 95%CI 1.08-4.38; p = 0.029). Conclusions. Regardless of age and previous cardiovascular events, post-RAO patients are at a higher risk of all-cause mortality than patients without a history of RAO.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Long-term mortality after retinal artery occlusion – a single centre study

Roskal-Wałek¹,

Mackiewicz²,

Wałek³

et al. 2023

Ann Agric Environ Med.

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“…12 This method has been used in previous studies. 15 , 16 , 17 , 18 Continuous variables are presented as means and SDs or medians and interquartile ranges (IQRs), and categorical variables are presented as percentages. Continuous variables were compared using the Wilcoxon rank sum test, whereas categorical variables were compared using the Pearson chi-square test.…”

Section: Methodsmentioning

confidence: 99%

Impact of Gender, Race, and Insurance Status on Inhospital Management and Outcomes in Patients With COVID-19 and ST-Elevation Myocardial Infarction (a Nationwide Analysis)

Patel

Majmundar

Vasudeva

et al. 2023

The American Journal of Cardiology

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“…N on-arteritic permanent central retinal artery occlusion (NA-CRAO) is a type of small vascular stroke [1][2][3][4][5][6][7][8][9][10][11][12] that typically results in severe vision loss. The gold standard for diagnosing retinal artery occlusion (RAO) is fluorescein fundus angiography (FFA) [13][14] .…”

Section: Introductionmentioning

confidence: 99%

OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity

Gong,

Xie,

Zhang

et al. 2024

Int J Ophthalmol

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AIM: To observe the retinal and choroidal circulations in patients with non-arteritic permanent central retinal artery occlusion (NA-CRAO) via optical coherence tomography angiography (OCTA) and analyze their correlation with visual acuity. METHODS: Sixty-two eyes with clinically confirmed acute NA-CRAO were included in the study and divided into: A type (mild n=29), B type (moderate n=27) and C type (severe n=6) based on the degree of visual loss, retinal edema, and arterial blood flow delay in fundus fluorescence angiography (FFA). Contralateral healthy eyes were used as the control group. Best-corrected visual acuity (BCVA), slit lamp microscopy, indirect ophthalmoscopy, fundus color photography, OCTA, and FFA were performed. Spearman’s correlation analysis was used to determine the correlations between retinal and choroidal vessels and visual acuity. RESULTS: There were no statistically significant differences in age, gender, and intraocular pressure among the three types and the control group (P>0.05). Vessel density in deep capillary plexus (VD-DCP) significantly decreased (P<0.05) in all three types of NA-CRAO patients compared to the control group. Vessel density in superficial vascular plexus (VD-SVP) significantly decreased (P<0.05) in type A patients and choriocapillaris flow area significantly decreased (P<0.05) in type B and type C patients compared to the control group; while outer retinal flow areas significantly increased in the type A (P<0.05) and decreased in type C patients (P<0.05). The retinal thickness significantly increased in type C group (P<0.05). The VD-SVP at fovea in the type A was significantly lower than both of type B and C. The VD-SVP at nasal parafovea in type A and B was significantly lower than type C (P<0.05). The logMAR BCVA of type A was significantly better than that of type B and C groups (P<0.05). Spearman’s correlation analysis showed that the logMAR BCVA was positively correlated with VD-SVP at fovea (r=0.679, P=0.031) and nasal parafovea (r=0.826, P=0.013). CONCLUSION: OCTA is valuable for assessing retinal ischemia, and evaluating visual impairment. Deep retinal vasculature is commonly affected in all NA-CRAO types. VD-SVPs at fovea and nasal parafovea can serve as reliable markers of visual impairment in NA-CRAO.

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Outcomes and Readmission in Patients With Retinal Artery Occlusion (from the Nationwide Readmission Database)

Cited by 6 publications

References 6 publications

Long-term mortality after retinal artery occlusion – a single centre study

Long-term mortality after retinal artery occlusion – a single centre study

Impact of Gender, Race, and Insurance Status on Inhospital Management and Outcomes in Patients With COVID-19 and ST-Elevation Myocardial Infarction (a Nationwide Analysis)

OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity

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