Outcomes and risk factors for ERCP-related complications in a predominantly black urban population

Abstract

ObjectiveThere is a lack of literature on postendoscopic retrograde cholangiopancreatography (ERCP) complications in predominantly black urban populations of low socioeconomic status. The aim of this study was to determine the incidence and predictors of post-ERCP complications in this patient population.DesignRetrospective review of ERCP cases performed at two hospitals from 2007 to 2017 was performed. The categories of complications evaluated were overall complications, severe or fatal complications, pancreatitis, bleeding, infection, perforation and cardiopulmonary events. Predictors of complications were determined by univariate analysis.ResultsA total of 1079 ERCP procedures were reviewed. There were 106 complications (9.8%). Twenty-one were severe (1.9%) and 20 were fatal (1.9%). Both post-ERCP pancreatitis (PEP) and post-ERCP bleeding occurred in 18 patients (1.7%) each. Risk factors for overall complications were male sex (OR 1.54), ASA grade IV or V (OR 2.19), prior history of PEP (OR 6.98) and pancreatic duct stent placement (OR 2.75). Those who were ASA grade III or lower (OR 0.4) or who underwent biliary stone extraction (OR 0.62) had fewer complications. PEP was more likely in those with a prior history of PEP (OR 37.6). Those with a suspected or known biliary duct stone had less frequent pancreatitis (OR 0.32). Post-ERCP bleeding was more likely in the presence of cholangitis (OR 8.72).ConclusionOutcomes of ERCP in a predominantly black urban population demonstrate a lower incidence of PEP and all-cause mortality compared with historical data reported in the general population. Potential risk factors for post-ERCP complications were identified but require larger studies for validation.

Technical Outcomes in Pediatric Endoscopic Retrograde Cholangiopancreatography: Data from an International Collaborative

“…Overall, this study demonstrated that severe adverse events related to pediatric ERCPs were uncommon, with overall rates of adverse events occurring in 9.7% of cases, which is similar to that of other retrospective adult and pediatric studies (27,32–34). Adverse events in this study included PEP, non‐PEP pain, bleeding, fever of unknown etiology, cholangitis, and perforation.…”

Endoskopik retrograd kolanjiyopankreatografinin endikasyonları, sonuçları ve komplikasyonları: Doğu Karadeniz'deki üçüncü basamak bir merkezin 3 yıllık verileri

“…İnvaziv bir girişim olması nedeniyle literatürde %10'lara ulaşan ERCP ilişkili komplikasyonlar bildirilmiştir (4,5). ERCP'nin en sık görülen komplikasyonları pankreatit, kanama, kolanjit, kolesistit ve perforasyondur (4,5). ERCP ile ilişkili komplikasyonları azaltmak için risk faktörlerinin çok iyi bilinmesi ve uygun endikasyonlarda ERCP yapılması önerilmektedir (5).…”

“…Indications, results, and complications of endoscopic retrograde cholangiopancreatography: 3-year data of a third-level center in the Eastern Black Sea Region İD Sami FİDAN, İD Arif Mansur COŞAR Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Gastroenteroloji Bilim Dalı, Trabzon yı 2-3 gün plansız hastanede yatması hafif, dört ila 10 gün yatması orta, 10 günden fazla yatması, cerrahi ya da invaziv radyolojik müdahale gereksinimi veya ölümle sonuçlanan komplikasyonlar ise ciddi komplikasyon olarak tanımlandı (4,5). ERCP ilişkili pankreatitin tanısı; uyumlu klinik ve/veya radyolojik bulguların varlığı ile birlikte serum amilaz düzeylerinin normal üst sınırın üç katından daha yüksek olması ile konuldu (5,13).…”

Cirugía de control de daños como manejo de lesión dudodenal secundaria a CPRE: a propósito de un caso

“…La CPRE, que se ha transformado de ser principalmente diagnóstica a una función fundamentalmente terapéutica (Johnson et al, 2020), es de uso diverso, asociándose sobre todo con trastornos pancreatobiliares. Este procedimiento fue inicialmente introducido en 1968 por McCune (Kwak et al, 2020).…”