Outcomes in 11 patients with dermatofibrosarcoma protuberans treated with Mohs micrographic surgery

Abstract

The recurrence potential of DFSP is directly related to the extent of resection. Mohs micrographic surgery with continuous histological margin control allows for maximum tissue preservation and low recurrence rates and is rapidly emerging as a first-line treatment modality for this condition.

Pediatric Dermatofibrosarcoma Protuberans in Madrid, Spain: Multi‐institutional Outcomes

“…Mohs micrographic surgery (MMS) is currently recommended as the treatment of choice for DFSP since it offers the highest cure rate, with a recurrence rate of 0% to 6.6% (38)(39)(40). If this technique is not available, wide surgical excision (2-4 cm) must be performed to ensure tumorfree margins.…”

Mohs micrographic surgery in dermatofibrosarcoma protuberans allows tumour clearance with smaller margins and greater preservation of healthy tissue compared with conventional surgery: a study of 74 primary cases

“…In 1996, Dawes and Hanke 27 reported that the mean amount of tissue spared by using MMS rather than CS with 3-cm margins in seven patients with DFSP lesions in cosmetically complicated locations was 43 cm 2 . More recently, Galimberti et al 28 reported that the mean size of a hypothetical defect created by CS with a margin of 3 cm was more than twice that of the defect created by MMS (17Á78 cm 2 vs. 7Á49 cm 2 ). While the value of these studies is unquestionable, their results have certain limitations.…”

Dermatofibrosarcoma Protuberans: A Case Report

“…The factors associated with high rates of recurrence are histological subtype, cellularity, size, location on the head and neck, and high mitotic rate [19, 20]. There are current reports praising the use of Mohs micrographic surgery as a first-line therapeutic measure in cases of limited tumors for tissue preservation and reduction of recurrence rate [4, 21, 22, 23]. …”