Prostate cancer (PCa) has been cited as the leading cancer in men in sub-Saharan Africa (SSA). Published data from a few registries in SSA suggest that the rates are still rising. Men In SSA are reported to be at higher risk of the disease, and are about twice as likely to die from prostate cancer than white men. Despite the achievement to reduce the incidence of PCa, globally, very little success has been reported in SSA. This study aimed to examine the status of PCa in SSA and describe its care, management and challenges. Data supporting this study were obtained through extensive internet search of articles, using specific search terns. The findings indicated that patients with PCa in SSA normally present for management at advanced stage of the disease. It is suggested that this could be due to lack of knowledge, insufficiently staffed facilities, perceptions by men toward PCa, and tests for the condition which are uncomfortable and do not conform to their culture. The search revealed challenges relating to health care system and socio-economic factors. There is a need to increase the knowledge on PCa among men in SSA, as well as for sufficient staffing and promotion of men-friendly services.