Outcomes in Patients with Minor Stroke: Diagnosis and Management in the Post-thrombectomy Era

Marsh, Elisabeth B.; Girgenti, Sophia; Llinas, Edward J.; Brunson, Autumn O

doi:10.1007/s13311-023-01349-5

Cited by 3 publications

(2 citation statements)

References 133 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With advances in stroke treatment, the average patient recovery level has improved, and the thresholds for assessing the success of procedures are increasing correspondingly. In the era of thrombectomy, experience shows that certain deficits that were once considered background issues must now be taken into consideration [1]. Among these deficits, cognitive and behavioural disorders are the most significant.…”

mentioning

confidence: 99%

“…A meta‐analysis [9] suggests that cognitive impairments and residual depressive states are common after strokes classified as minor. A whole range of deficits that do not affect motor function can occur even after a minor stroke [1]. These subtle deficits are challenging to assess and may be neglected when assessing functional outcomes using conventional tools and scales.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Basal ganglia matter

Viader

2023

Euro J of Neurology

View full text Add to dashboard Cite

mentioning

confidence: 99%

mentioning

confidence: 99%

Basal ganglia matter

Viader

2023

Euro J of Neurology

View full text Add to dashboard Cite

Longitudinal outcomes of ischemic versus hemorrhagic stroke: Differences may impact future trial design

Girgenti,

Lu,

Marsh

2024

Journal of Stroke and Cerebrovascular Diseases

View full text Add to dashboard Cite

Modified-Mindfulness-Based Stress Reduction as a Treatment for Cognitive Recovery in Patients with Minor Stroke: a Randomized Controlled Pilot Study

Girgenti,

Dallasta,

Lawrence

et al. 2024

Preprint

View full text Add to dashboard Cite

Background: Well-developed rehabilitation paradigms exist for post-stroke language and motor impairments. However, no such recovery program has been identified for commonly disabling cognitive deficits in patients following minor stroke. Mindfulness Based Stress Reduction (MBSR) is thought to engage the frontal lobes, improving concentration and attention, and therefore may be an effective option. Methods: We prospectively enrolled a cohort of patients with subacute minor stroke and randomized them to either an 8-week online modified-MBSR course or online traditional Stroke Support Group (SSG). All patients underwent a battery of cognitive tests and measures of patient reported outcomes (PROs) pre- and post-intervention. ANOVA was used to compare changes in scores over time across both groups, as well as a third group of control patients having received neither intervention (n=128). Results: A total of 30 patients were randomized (n=16 for m-MBSR; n=14 for SSG). The average age of the cohort was 65.9 years. Both groups scored similarly on assessments one-month post-stroke and demonstrated increased T-scores on cognitive tasks at the 3-month visit. However, the m-MBSR group showed moderately elevated levels of improvement, specifically in processing speed, executive, and global cognitive function. Level of engagement was not associated with better clinical scores, though was unexpectedly low for both groups. Conclusions: m-MBSR appears to modestly improve frontal lobe activity and demonstrates some success in increasing cognitive performance. However, further studies are needed to determine if it is more efficacious in the chronic stage of recovery when more patients are able to fully engage and actively participate.

show abstract

Outcomes in Patients with Minor Stroke: Diagnosis and Management in the Post-thrombectomy Era

Cited by 3 publications

References 133 publications

Basal ganglia matter

Basal ganglia matter

Longitudinal outcomes of ischemic versus hemorrhagic stroke: Differences may impact future trial design

Modified-Mindfulness-Based Stress Reduction as a Treatment for Cognitive Recovery in Patients with Minor Stroke: a Randomized Controlled Pilot Study

Contact Info

Product

Resources

About