Outcomes of Anticoagulation for Portal and/or Splenic Vein Thrombosis in Setting of Acute Pancreatitis

Anderson, W. S.; Niccum, Blake; Chitnavis, Maithili V.; Uppal, Dushant; Hays, Ann R.

doi:10.14309/00000434-201710001-00011

Cited by 8 publications

(20 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After critical review, 18 observational (15 retrospective and 3 prospective) studies published between 2008 and 2020 met the inclusion criteria. 1,3,4,8,[19][20][21][22][23][24][25][26][27][28][29][30][31][32] Seven of these studies were published only in abstract form. [21][22][23][24][25]31,32 The studies originated from North America (n = 9), Europe (n = 6), and Asia (n = 3) (Table 1).…”

Section: Resultsmentioning

confidence: 99%

Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta‐analysis

Anis

Adiamah

Lobo

et al. 2021

J of Gastro and Hepatol

View full text Add to dashboard Cite

Background and Aim:This meta-analysis aimed to estimate the incidence of splanchnic vein thrombosis (SVT) in patients with acute pancreatitis and assess the effects of therapeutic anticoagulation. Methods: Systematic searches of the Medline, Embase, and Cochrane databases were undertaken to identify studies reporting the incidence and outcomes associated with SVT in patients with acute pancreatitis. The pooled incidence, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random effects model. PROSPERO database registration no. CRD 42021230912. Results: Only 18 of the 238 studies identified met the inclusion criteria. Of the 943 patients who had SVT, 264 (28.0%) received anticoagulation. The pooled incidence of SVT at first presentation of acute pancreatitis was 15% (95% CI 5 to 26%), but was 17% (95% CI 14 to 20%) in all studies. Recanalization was more likely to occur in the anticoagulation-treated than in the untreated group (OR 0.51, 95% CI 0.31 to 0.83, P = 0.007). There were no differences in hemorrhagic complications (OR 2.27, 95% CI 0.81 to 6.37, P = 0.12) or overall mortality (OR 2.37, 95% CI 0.86 to 6.52, P = 0.10) in relation to the use of anticoagulation. The overall incidence of portal hypertension in patients was 60% (95% CI 55 to 65%). However, it was not possible to determine the incidence in each group. Conclusions: The incidence of SVT in patients with acute pancreatitis is significant. Treatment with anticoagulants improved the odds of recanalization but did not increase the risk of hemorrhagic complications or overall mortality.

show abstract

Section: Resultsmentioning

confidence: 99%

Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta‐analysis

Anis

Adiamah

Lobo

et al. 2021

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

“…The etiology of his AKI was likely multifactorial, and the differential diagnosis includes AKI secondary to ischemic acute tubular necrosis in the setting of hemorrhagic shock versus secondary to nephrotoxin exposure (IV contrast for CT scans). It was likely further exacerbated by the use of vasopressors [ 8 ]. The patient was initially started on continuous venovenous hemodialysis (CVVHD), a type of CRRT, through a non-tunneled dialysis catheter, however, the circuit clotted hours into the dialysis session.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Rapidly Transforming Pancreatitis With Life-Threatening Complications and Multi-Organ Failure

Ahmed¹,

Grifith²,

Lipshutz³

et al. 2021

Cureus

View full text Add to dashboard Cite

Acute pancreatitis affects approximately 50,000-80,000 Americans each year. Eighty percent of those cases are related to alcohol use or biliary stones. It has traditionally been thought of as a self-limiting disease, in which the pancreas fully recovers with little or no intervention. The occurrence of complications, particularly infectious ones, characterize the most severe forms of acute pancreatitis and is associated with high mortality. We present a case of acute pancreatitis with transformation into necrotizing and hemorrhagic pancreatitis complicated with splenic vein thrombosis (SVT), acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and later, fungemia.

show abstract

“…Although venous thrombosis may be asymptomatic at diagnosis, it is important to detect because progression can result in portomesenteric venous obstruction and associated complications such as severe hemorrhage, portal hypertension, and bowel infarct [32,33]. Additionally, identification of venous thrombosis on imaging guides clinical consideration of the appropriateness of anticoagulation, which must be weighed against increased bleeding risk [34]. While lacking consensus, anticoagulation may be Arterial pseudoaneurysm is a less frequent complication of acute pancreatitis and occurs in up to 10% of patients [32,35].…”

Section: Vascular Complicationsmentioning

confidence: 99%

Multidisciplinary Management of Complicated Pancreatitis: What Every Interventional Radiologist Should Know

Rahnemai‐Azar

Sutter

Hayat

et al. 2021

American Journal of Roentgenology

View full text Add to dashboard Cite

The publication of this Accepted Manuscript is provided to give early visibility to the contents of the article, which will undergo additional copyediting, typesetting, and review before it is published in its final form. During the production process, errors may be discovered that could affect the content of the Accepted Manuscript. All legal disclaimers that apply to the journal pertain. The reader is cautioned to consult the definitive version of record before relying on the contents of this document.

show abstract

Outcomes of Anticoagulation for Portal and/or Splenic Vein Thrombosis in Setting of Acute Pancreatitis

Cited by 8 publications

References 0 publications

Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta‐analysis

Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta‐analysis

A Rare Case of Rapidly Transforming Pancreatitis With Life-Threatening Complications and Multi-Organ Failure

Multidisciplinary Management of Complicated Pancreatitis: What Every Interventional Radiologist Should Know

Contact Info

Product

Resources

About