Outcomes of Atrial Fibrillation Ablation in Patients With and Without Chronic Kidney Disease Are No Different…. . Hmmm!

Deshmukh, Abhishek; Kancharla, Krishna

doi:10.1111/jce.13123

Cited by 2 publications

(1 citation statement)

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“…A study by Deshmukh et al, analyzed 93,801 CA procedures of which only 11.7% were performed in patients aged greater than 80 years. The study found that older patients aged greater than 80 years had a higher complication rate in comparison to younger patients . The study had some limitations as it did not report mortality outcomes, it only looked at overall complications and did not divide them into minor or major complications.…”

Section: Introductionmentioning

confidence: 99%

Safety of catheter ablation for atrial fibrillation in the octogenarian population

Romero

Ogunbayo²,

Elayi³

et al. 2019

Cardiovasc electrophysiol

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Introduction Catheter ablation (CA) has been shown to be an effective treatment for atrial fibrillation (AF). The complication rates and outcomes among octogenarians remain poorly studied. We aimed to compare trends, morbidity, and mortality associated with CA for AF among octogenarians versus those less than 80 years old. Methods Using weighted sampling from the National Inpatient Sample database, we identified patients with a primary diagnosis of AF and a primary procedure of CA (2004‐2013). Our primary outcome was mortality. Secondary outcomes included incidence of major and minor complications. Results Among 86,119 patients who underwent CA for AF, 3,482 were 80 years old or older. Complications were significantly more frequent in octogenarians; [16.2% (564 of 3,482) versus 9.8% (8,092 of 82,637), P < 0.001]. Of note, there was no significant difference for the composite of major complications; [3.6% (124 of 3482) in octogenarians versus 2.8% (2286 of 82637), P = 0.20]. The total mortality rate was not significant in a multivariate regression analysis (odds ratio [OR], 0.96; 95% confidence interval [CI], 0.35‐2.64; P = .94). The presence of chronic renal failure (OR, 4.19; 95% CI, 2.75‐6.36; P < 0.001), anemia (OR, 1.75; 95% CI, 1.03‐2.97; P = .04), and chronic pulmonary disease (OR, 1.75; 95% CI, 1.11‐2.62; P = .015) were predictors of major complications in octogenarians. Conclusion Catheter ablation for AF in octogenarians does not confer a higher mortality risk than in those less than 80 years old. The procedure is associated with a higher rate of overall complications but there was no difference in terms of major complications or death. The presence of anemia, CKD or pulmonary disease were predictors of major complications in octogenarians.

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Section: Introductionmentioning

confidence: 99%