Outcomes of death and prolonged renal insufficiency in ethylene glycol poisoned patients

Grigorași, Gabriela; Nistor, Ionuţ; Corlade-Andrei, Mihaela; Voroneanu, Luminița; Siriopol, Dimitrie; Apetrei, Mugurel; Cimpoeşu, Diana; Covic, Adrian

doi:10.1007/s11255-021-02837-3

Cited by 4 publications

(17 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Introductionmentioning

confidence: 99%

“… 9 Without sufficient care, MET and EG poisoning result in significant morbidity and mortality. 8 – 10…”

Section: Introductionmentioning

confidence: 99%

“… 11 Even with sufficient treatment, MET and EG poisoning are associated with poor survival, often because of late presentation. 9 , 12 …”

Section: Introductionmentioning

confidence: 99%

“…7,8 MET poisoning typically results in visual impairment and central nervous system damage, 8 whereas AKI is more typical in EG poisoning. 9 Without sufficient care, MET and EG poisoning result in significant morbidity and mortality. [8][9][10] The primary aim of RRT in patients with MET or EG poisoning is to promptly remove the toxin and its injurious metabolites.…”

Section: Introductionmentioning

confidence: 99%

“…9 Without sufficient care, MET and EG poisoning result in significant morbidity and mortality. [8][9][10] The primary aim of RRT in patients with MET or EG poisoning is to promptly remove the toxin and its injurious metabolites. The preferred RRT modality is intermittent hemodialysis (IHD).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Mortality and associated risk factors in patients with severe methanol or ethylene glycol poisoning treated with dialysis: a retrospective cohort study

et al. 2022

View full text Add to dashboard Cite

Objective To compare the initial clinical course and data on 90-day mortality in adults with methanol (MET) or ethylene glycol (EG) poisoning treated with dialysis. Methods Data on patient demographics and clinical parameters at intensive care unit (ICU) admission and for the first 24 hours after dialysis initiation were collected, and 90-day outcome data were collected for patients with MET (n = 15) or EG (n = 13) poisoning treated with dialysis in this retrospective cohort study. Results In univariate analysis, patients with EG poisoning were older and they had lower hourly urine output during the first 24 hours after the initiation of dialysis. Six (46%) patients with MET poisoning and three (20%) patients with EG poisoning died within 90 days of ICU admission. A larger anion gap and lower pH, bicarbonate levels, base excess, and Glasgow Coma Scale scores on admission, as well as the need for mechanical ventilation, were associated with 90-day mortality. Conclusions Metabolic acidosis, a large anion gap, and an altered mental status on admission appear to be associated with mortality in MET or EG poisoning, and EG poisoning may be linked to lower urine output.

show abstract