Outcomes of Early Liver Transplantation in a Hospital That Is Starting to Perform Liver Transplantation

Lee, Eun Kyoung; Chang, Shih-Chieh; Kim, Duk Kyung; Cheon, Bo Sung; Hong, Young-Sang; Kang, Byoung Joon; Nam, Sang Eun; Sim, Jae Hoon; Lee, Hae-Won; Yun, Ik Jin

doi:10.4285/jkstn.2011.25.3.184

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Even though liver transplantation became the standard treatment for ESLD and early-stage HCC and the number of liver transplant programs is rapidly increasing all over the world, there are a limited number of recent publications about outcomes from new liver transplant programs [ 9 , 10 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia

Kim

Jung

et al. 2014

Ann Surg Treat Res

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PurposeTo evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors.MethodsMedical records of initial 50 liver transplantations were reviewed retrospectively.ResultsTwenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 ± 11.6 and 13.1 ± 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8%, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT.ConclusionAs a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.

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Section: Discussionmentioning

confidence: 99%

Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia

Kim

Jung

et al. 2014

Ann Surg Treat Res

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Anesthetic Experiences of Liver Transplantation in a New Low Volume Hospital: Ewha Womans University Mokdong Hospital

et al. 2017

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Objectives: Liver transplantation (LT) is the only treatment for end stage of liver failure. In Korea, annually it has been performed 1,300 cases. Most of LTs are performed in large volumes centers. More than half of centers performing LT in Korea are low volume hospital and started a LT program recently. We present our four-year experiences and outcomes of anesthesia for LT since 2013. Methods: Anesthetic and surgical outcomes of 49 consecutive patients who received LT (living donor LT, 21 cases; deceased donor LT, 28 cases) between April 2013 and April 2017 were analyzed retrospectively. Results: All patients were adult, with the mean age of 53.5±9.2 years. The most common cause of original liver diseases was hepatitis B virus-related liver cirrhosis (40.8%). The mean MELD (Model for End-stage Liver Disease) score was 18.8±10.7. Postreperfusion syndrome was observed in 34.7%, which were all controlled by calcium, norepinephrine, ephedrine and epinephrine. The mean postoperative intensive care unit stay of deceased donor LT recipients (13.6±9.0 days) was significantly longer than that of living donor LT recipients (8.0±3.3 days). There was no intraoperative mortality in patients receiving LT. Thirty-day post-transplant survival rate was 93.8% and 3-year survival rate was 88.6 %. The most common postoperative complication was pneumonia.

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Outcomes of Early Liver Transplantation in a Hospital That Is Starting to Perform Liver Transplantation

Cited by 2 publications

References 11 publications

Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia

Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia

Anesthetic Experiences of Liver Transplantation in a New Low Volume Hospital: Ewha Womans University Mokdong Hospital

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