2019
DOI: 10.1007/s00405-019-05308-9
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Outcomes of endoscopic sinus surgery in adult lung transplant patients with cystic fibrosis

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Cited by 17 publications
(23 citation statements)
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“…Our findings, which include a much larger series, are consistent with this study. 6 On regression analysis, we found that patients with pseudomonas on culture had less improvement on SNOT-22 after ESS. This is not surprising given the refractory nature of pseudomonas and prior evidence showing that pseudomonas is associated with worse baseline sinonasal symptoms in CF.…”
Section: Discussionmentioning
confidence: 82%
“…Our findings, which include a much larger series, are consistent with this study. 6 On regression analysis, we found that patients with pseudomonas on culture had less improvement on SNOT-22 after ESS. This is not surprising given the refractory nature of pseudomonas and prior evidence showing that pseudomonas is associated with worse baseline sinonasal symptoms in CF.…”
Section: Discussionmentioning
confidence: 82%
“…The goals of surgery are to reduce sinonasal symptoms and remove bacterial reservoirs that are believed to contribute to acute pulmonary exacerbations and decline in lung function 5,6,22,38 . However, the published results are somehow conflicting, 21,38–40 and a recently published meta‐analysis that included 570 patients did not find any improvement in pulmonary function after ESS 41 …”
Section: Discussionmentioning
confidence: 99%
“…6 The goals of surgery are to reduce sinonasal symptoms and remove bacterial reservoirs that are believed to contribute to acute pulmonary exacerbations and decline in lung function. 5,6,22,38 However, the published results are somehow conflicting, 21,[38][39][40] and a recently published meta-analysis that included 570 patients did not find any improvement in pulmonary function after ESS. 41 The reduced sinus pneumatization was experimentally induced in animal studies through the alteration of the CFTR gene and with the fundamental contribution of chronic infection and inflammation that begin since birth.…”
Section: Discussionmentioning
confidence: 99%
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“…(263,264) Although data supporting pre-transplant sinus surgery are lacking, optimization of sino-nasal management prior to transplant should be thoroughly considered given the high incidence of sinus disease and potential post-transplant implications. (264)(265)(266)(267) Non-infectious comorbidities include malnutrition, which is common in CF patients approaching transplant and represents a potentially modifiable risk factor. A low BMI is associated with lung function decline and mortality in advanced CF lung disease.…”
Section: Special Considerations In Cystic Fibrosismentioning
confidence: 99%