2009
DOI: 10.1111/j.1600-6143.2009.02643.x
|View full text |Cite
|
Sign up to set email alerts
|

Outcomes of Heart Transplantation for Cardiac Amyloidosis: Subanalysis of the Spanish Registry for Heart Transplantation

Abstract: Amyloidosis (Am), a systemic disease, has poor prognosis because of organ damage produced by protein deposition in the extracellular space. Although heart transplantation (HTx) is possible, donor availability concerns and high mortality make this approach controversial. The Spanish Registry for Heart Transplantation includes 25 Am patients (54 ± 9 years): 13 with AL type, 2 with AA and 10 with TTR mutation. Fifteen patients (60%) died during follow-up (4.9 ± 1.3 years): 9 AL-Am patients, both AA-Am patients an… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

1
28
0
5

Year Published

2009
2009
2023
2023

Publication Types

Select...
4
3
1

Relationship

0
8

Authors

Journals

citations
Cited by 53 publications
(34 citation statements)
references
References 25 publications
1
28
0
5
Order By: Relevance
“…The authors included all types of amyloid and did not detail treatment for the underlying disease [126]. Data from other registries suggests poorer prognosis for patients transplanted with AL amyloidosis compared to other types of cardiac amyloidosis [127]. As described above, survival may be improved if bone marrow transplantation is performed after cardiac transplant.…”
Section: Outcomes Of Heart Transplant In Al Cardiac Amyloidosismentioning
confidence: 99%
“…The authors included all types of amyloid and did not detail treatment for the underlying disease [126]. Data from other registries suggests poorer prognosis for patients transplanted with AL amyloidosis compared to other types of cardiac amyloidosis [127]. As described above, survival may be improved if bone marrow transplantation is performed after cardiac transplant.…”
Section: Outcomes Of Heart Transplant In Al Cardiac Amyloidosismentioning
confidence: 99%
“…We read with interest the series about heart transplantation for cardiac amyloidosis from the Spanish Registry for heart transplantation (1) (2).…”
Section: Outcomes Of Heart Transplantation For Cardiac Amyloidosis: Smentioning
confidence: 99%
“…Cardiac transplantation has been demonstrated to have beneficial effect on 1-5 year survival rates of 40-89.5% on patients with RCM. However, patients with RCM due to radiation [106,108,111] or amyloidosis [107,109] have poorer outcomes suggesting the need to consider genetic or idiopathic RCM for cardiac transplantation due to shortages and long wait times for donors. However, patient selection and aggressive therapies to reduce amyloid depositions on myocardial tissues suggest improvement of short-term (380 days) survival rates [110].…”
Section: Study Characteristics and Outcomesmentioning
confidence: 99%
“…After screening, titles, abstracts and full article against the inclusion criteria, eight (8) studies were included [105][106][107][108][109][110][111][112] published between 2002 and 2016. In total, the eight studies recruited 87,410 patients.…”
Section: Study Characteristics and Outcomesmentioning
confidence: 99%
See 1 more Smart Citation