In the context of existing theory and research, strategies and processes that may contribute to resilience and coping among lesbian, gay, and bisexual (LGB) individuals in the face of devaluing, prejudice, and discrimination are examined. Resilience is positive adaptation and development under conditions of risk and adversity (Luthar & Cicchetti, 2000; Rutter, 2012; Shiner & Masten, 2012). Attempts to maintain health and well-being are shaped as a function of the social environment resources available to LGB individuals at a given time and individuals’ personal characteristics. Social environment resources include interpersonal (social support), institutional (school, workplace, and governmental support), and community resources. Personal characteristics identified as likely to influence the types of emotion regulation strategies employed are social motivation, emotional openness, hope and optimism, and positive LGB identity, in addition to the Five Factor Model traits (Costa & McCrae, 1992) and coping styles (Carver & Scheier, 1994; Zeidner & Endler, 1996). A variety of emotion regulation strategies may be enlisted within heterosexist situations to diminish the experience of negative emotions, and increase or enhance the experience of positive emotions.