Outcomes of interval appendectomy in comparison with appendectomy for acute appendicitis

Al-Kurd, Abbas; Mizrahi, Ido; Siam, Baha; Kupietzky, Amram; Hiller, Nurith; Beglaibter, Nahum; Eid, Ahmed; Mazeh, Haggi

doi:10.1016/j.jss.2018.01.012

Cited by 26 publications

(14 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This rate is considerably higher than the morbidity rate of EA in the present study, but it is lower than that of CA in the present study. One retrospective study showed that the morbidity rate was 5.7% (6/106) 39 , which is almost the same as our result of EA. Only a large, randomized, controlled study can resolve this complex and important clinical question.…”

Section: Discussionsupporting

confidence: 88%

Risk of emergency surgery for complicated appendicitis: Japanese nationwide study

Yamada

Endo

Hasegawa

et al. 2020

Annals of Gastroent Surgery

View full text Add to dashboard Cite

Aim Appendicitis is divided into two categories: complicated appendicitis (CA) and uncomplicated appendicitis (UA). In pediatric patients with CA, the use of interval appendectomy (IA), which is non‐operative management followed by elective surgery, has decreased the number of postoperative complications. Before discussing the merit of IA for adult patients, we need to clarify whether the frequency and seriousness of the complication rate after emergency surgery is higher for CA than for UA. Methods This retrospective cohort study included adult patients who underwent appendectomy and who were registered in the National Clinical Database (NCD) from 2014 to 2016. Patients with CA who underwent emergency appendectomy comprised the CA group. Patients with UA comprised the UA group. Patients with chronic or recurrent appendicitis who underwent elective appendectomy comprised the elective appendectomy (EA) group. Primary outcomes were all morbidity, serious morbidity, and mortality within 30 days after appendectomy. Results We included 109 256 patients in the study: 14 798 CA, 86 876 UA, and 7582 EA patients. Compared with the UA group, the rates of all morbidity, serious morbidity, and mortality were significantly higher in the CA group. All morbidity, serious morbidity, and mortality rates were significantly lower in the EA group than in the other two groups. Conclusions We confirmed that emergency surgery for CA places the patient at relatively higher risk. We also showed that the risk associated with EA is significantly lower than that for the other methods.

show abstract

Section: Discussionsupporting

confidence: 88%

Risk of emergency surgery for complicated appendicitis: Japanese nationwide study

Yamada

Endo

Hasegawa

et al. 2020

Annals of Gastroent Surgery

View full text Add to dashboard Cite

show abstract

“…So, to overcome the problem of missing any small indolent slow growing neoplastic lesion within appendix, it may be a reasonable approach to carryout an interval appendicectomy at a later date. Not only ANENs have been demonstrated incidentally in appendicectomy specimens for acute appendicitis, it's also been reported as incidental findings discovered on histology of interval appendicectomy specimens too, without any clinical suspicion of any neoplasia (6,21,22). Hence, we strongly support the idea of interval appendicectomy rather than managing it completely conservatively…”

Section: Discussionsupporting

confidence: 68%

“…However, treating acute appendicitis with antibiotic only approach would be missing appendiceal tumours, found incidentally in appendicectomy specimens, which are predominantly appendiceal neuroendocrine neoplasms (ANEN). These are rare, slow growing, usually asymptomatic tumours, discovered incidentally in an appendicectomy specimens, carried out both as an emergency procedure, and in an electively performed interval appendicectomy specimens too (6)(7)(8). If treated early, an index appendicectomy is the curative treatment for the majority of incidental ANEN (7).…”

Section: Introductionmentioning

confidence: 99%

Appendicular Neuroendocrine Neoplasm is Associated with Acute Appendicitis - Don't Miss the Boat

Khan¹,

Patil²,

Roomi³

et al. 2019

chr

View full text Add to dashboard Cite

Chirurgia, 114 (4), 2019 trei (27.27%) au fost urmăriţi prin efectuarea unui CT la doi ani de la intervenţie, neexistând nici o recidivă. Concluzii: Apendicectomia este procedura de elecţie pentru majoritatea ANEN. După cum arată studiul nostru, în cazul în care apendicita acută este tratată folosind doar tratament conservator, există un risc mai scăzut de 1% de a rata diagnosticarea ANEN. De asemenea, doi dintre pacienţi sufereau de afecţiuni locale avansate. Acestea ar fi putut avea cu siguranţă un prognostic rezervat în lipsa apendicectomiei.

show abstract

“…The treatment strategies for acute appendicitis are controversial [5][6][7][8]. EA has not been recommended for complicated appendicitis because it increases the incidence of extended resection and postoperative complications.…”

Section: Discussionmentioning

confidence: 99%

Periappendiceal Fluid Collection on Preoperative Computed Tomography Can be an Indication for Interval Appendectomy: a Retrospective Study

Kanaka

Mizutani

Yokoyama

et al. 2022

Preprint

View full text Add to dashboard Cite

Background: The treatment strategies for acute appendicitis, such as emergency appendectomy (EA), interval appendectomy (IA), and repeating nonoperative management (NOM), are controversial. In this study, we examined the preoperative factors that can be used to distinguish which patients should undergo IA.Methods: We retrospectively identified 902 patients who underwent surgery for appendicitis in our hospital from January 2010 to December 2021. Of these patients, 776 were included in this study. The patients were divided into two groups: those with a periappendiceal fluid collection (PAFC) on preoperative computed tomography (PAFC-positive group, n = 170) and those without a PAFC (PAFC-negative group, n = 606). In each group, we compared patients who underwent EA and IA.Results: In the PAFC-positive group, patients who underwent EA had a significantly higher postoperative complication rate than those who underwent IA (40.5% vs. 24.0%, p = 0.037). In the multivariate analysis, only the presence of PAFC was significantly associated with an increased risk of postoperative complications (odds ratio, 7.11; 95% confidence interval, 2.73–18.60; p < 0.001). The presence of PAFC alone was not significantly associated with an increased risk of IA or NOM failure (odds ratio, 1.48; 95% confidence interval, 0.19–11.7; p = 0.71). The rate of neoplasia on pathologic examination was significantly higher in the PAFC-positive than PAFC-negative group (7.6% vs. 1.5%, p < 0.001); the rate of carcinoma was also higher in the PAFC-positive group (2.4% vs. 0.17%, p = 0.02).Conclusions: The presence of PAFC on preoperative computed tomography was found to be a risk factor for postoperative complications but not IA or NOM failure. It was also correlated with neoplasia as the etiology of appendicitis. Therefore, PAFC positivity is useful as an indication for IA.

show abstract

Outcomes of interval appendectomy in comparison with appendectomy for acute appendicitis

Cited by 26 publications

References 15 publications

Risk of emergency surgery for complicated appendicitis: Japanese nationwide study

Risk of emergency surgery for complicated appendicitis: Japanese nationwide study

Appendicular Neuroendocrine Neoplasm is Associated with Acute Appendicitis - Don't Miss the Boat

Periappendiceal Fluid Collection on Preoperative Computed Tomography Can be an Indication for Interval Appendectomy: a Retrospective Study

Contact Info

Product

Resources

About