Outcomes of laparoscopic hepatic resection versus percutaneous radiofrequency ablation for hepatocellular carcinoma located at the liver surface: A case-control study with propensity score matching

Abstract

LH is an effective treatment for surface HCC with regard to control of local recurrence.

Contrast-enhanced ultrasound-guided feeding artery ablation as add-on to percutaneous radiofrequency ablation for hypervascular hepatocellular carcinoma with a modified ablative technique and tumor perfusion evaluation

“…This result was comparable to the previous FAA study using CEUS guidance (8.5%) [15], and superior to others using Doppler guidance (13.5-17.6%) [12][13][14]. In general, cumulative LTP rates at 3 years ranged from 10.0% to 38.6% in conventional RFA of HCC [36][37][38]. It seemed that FAA-RFA offered better local tumor control than older methods, especially facilitated by CEUS.…”

Personalized treatment of patients with very early hepatocellular carcinoma

“…There are, however, some critical locations such as surface lesions and tumors close to organs or blood/biliary vessels that can make ablation challenging. These 'high risk' locations decrease the oncologic efficacy of RFA and the safety of the procedure [72][73][74].…”

Liver resection for recurrent hepatocellular carcinoma after radiofrequency ablation therapy

“…Despite the relatively high curative rate of RFA, some patients still have local recurrence burden, and repeated RFA is effective for such patients . However, the penetration of the deployed expandable needles into a small portal branch could lead to intraportal tumor shedding.…”

“…However, treatment outcomes after RFA can be influenced by physicians’ expertise. Local recurrence rates after RFA vary from 2.4% to 36%, and its incidence was higher in patients undergoing RFA compared with those undergoing liver resection . Furthermore, tumor seeding after RFA is common even in a high‐volume center (0.7% to 1.4%) and is associated with subcapsular location, poorly differentiated HCC, and high level of serum α‐fetoprotein …”