Outcomes of medical and surgical treatment for lower urinary tract symptoms (benign prostatic obstruction) - a population-based cohort study

Abstract

In this population-based study, operative treatment seemed to relieve LUTS, whereas medical treatment only slowed down their progression. These findings suggest that men with surgical treatment experience a more favourable outcome in LUTS than those receiving medical treatment.

Development and validation of a reversed-phase HPLC method for simultaneous determination of doxazosin mesylate and finasteride

“…Prostate overgrowth leads to urethral compression causing a partial or total urethral obstruction that interferes with normal urinary flow. The main symptoms are urinary hesitance, postvoid dribbling, increased risk of urinary tract infection, and urinary retention [2,3]. The two commonly used pharmacological classes of drugs for management of BPH are the α-1 adrenergic antagonists, such as doxazosin mesylate, and 5-α reductase inhibitors, such as finasteride, alone or in combination [4].…”

Additional correction of OAB symptoms by two anti-muscarinics for men over 50 years old with residual symptoms of moderate prostatic obstruction after treatment with Tamsulosin

“…Benign prostatic obstruction (BPO) is a pretty widespread abnormal state in men over 50 years old, and its frequency increases in association with ageing [1][2][3]. Symptoms of BPO can be very troublesome for people over 50 years old and affect quality of their lives [4].…”