Outcomes of Patients in Long-Term Opioid Maintenance Treatment

Zippel-Schultz, Bettina; Specka, Michael; Cimander, Konrad; Eschenhagen, Thomas; Gölz, Jörg; Maryschok, Markus; Nowak, Manfred; Poehlke, Thomas; Stöver, Heino; Helms, Thomas M.; Scherbaum, Norbert

doi:10.1080/10826084.2016.1188946

Cited by 23 publications

(14 citation statements)

References 35 publications

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“…Long-term studies of OMT patients have shown the longer the duration of treatment, the more stabilized a patient remains (Appel et al, 2001;Zippel-Schultz et al, 2016). For inpatients, the goal is to complete a distinct course of treatment.…”

Section: Sud Treatment Approachesmentioning

confidence: 99%

Building abstinent networks is an important resource in improving quality of life

Muller

Clausen

2017

Drug and Alcohol Dependence

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Section: Sud Treatment Approachesmentioning

confidence: 99%

Building abstinent networks is an important resource in improving quality of life

Muller

Clausen

2017

Drug and Alcohol Dependence

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“…Although substitution treatment makes a substantial contribution to ensuring patients' survival (23), only some 4% of patients per year successfully complete treatment (24)(25)(26). At the same time, there is evidence in the literature of a decline in new cases of opioid-related disorders in Europe (27)(28)(29).…”

Section: Discussionmentioning

confidence: 99%

Estimation of the Number of People With Opioid Addiction in Germany

Kraus¹,

Seitz²,

Schulte³

et al. 2019

Deutsches Ärzteblatt International

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pioid addiction is one of the most common substance-related disorders worldwide. It is responsible for the majority of the morbidity and mortality caused by drugs in the population (1). Opioids include both synthetic (e.g. heroin, methadone, buprenorphine, fentanyl) and plant-derived substances (opiates, e.g. codeine and morphine). Opioids carry major risks of physical and pharmacological dependency (2). Intravenous use, in particular, is associated with a nonnegligible risk of communicable diseases (3) or death due to overdose or the long-term consequences of use (4). Finally, there is an increased risk of criminal behavior, specifically drug-related crime (5). Knowing how many individuals are addicted to opioids is important for setting health policy (6). In the first instance, calculations in Germany concern addiction caused by taking illegal opioid-containing substances. A preliminary national estimate for Germany as a whole in 1989, based on treatment data, gave a figure of 60 000 to 80 000 individuals who were problem users of opiates, cocaine, stimulants, or hallucinogenic drugs (7). A German expert group estimated the number of heroin users in western and eastern Germany in 1995 at 127 000 to 152 000 (8); for the same year, the number of intravenous drug users in western Germany and Berlin was estimated at a mean of 150 000 (97 000 to 204 000) on the basis of a survey among general practitioners (9). As part of estimating the number of individuals with problematic drug use in European Union countries, figures of 127 000 to 190 000 opiate users in Germany for the year 2000 were found using various methods. This calculation was based on treatment, police, and mortality data (10). Using these approaches, comparative estimates for 1990, 1995, and 2000 indicated a moderate increase in the number of opiate users (11). The aim of this study was to estimate the number of individuals addicted to opioids in Germany and its individual federal states for the calendar year 2016. Method This estimate is based on substitution treatment registry data, data from inpatient and outpatient addiction care statistics, and counts in 5 low-threshold addiction care Summary Background: Opioid addiction is one of the most common substance-related disorders worldwide, and morbidity and mortality due to opioid addiction place a heavy burden on society. Knowing the size of the population that is addicted to opioids is a prerequisite for the development and implementation of appropriate health-policy measures. Methods: Our estimate for Germany for 2016 is based on an enumeration of opioidaddicted persons who were entered in a registry of persons receiving substitution therapy, an enumeration of persons receiving outpatient and inpatient care for addiction without substitution therapy, an extrapolation to all addiction care facilities, and an estimation of the number of opioid-addicted persons who were not accounted for either in the substitution registry or in addiction care. Results: The overall estimate of the number of opioid-addict...

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“…Für die Mehrheit dieser in chronischen Problemsituationen befindlichen Patienten ist die Substitutionsbehandlung zeitlich nicht limitiert. Nach der PREMOS-Studie gibt es sogar Hinweise, dass Praxen mit einer deutlichen Abstinenzorientierung (einschließlich der Abstinenz vom Substitutionsmittel) schlechtere Behandlungsergebnisse erzielten als die übrigen Praxen [12]. Zudem unterliegen Patienten nach Ende einer Substitution einem erheblich gesteigerten Mortalitätsrisiko im Vergleich zu Patienten, die in Substitution verbleiben [15].…”

Section: Analyse Der Studienbeenderunclassified

Ergebnisse der langjährigen Substitutionsbehandlung Opiatabhängiger – die SubsCare-Studie

et al. 2018

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Zusammenfassung Ziel Erhebung des gesundheitlichen und sozialen Zustands von mehr als 5 Jahre opiatsubstituierten Patienten. Methodik 130 Patienten aus 12 Praxen wurden über 2 Jahre beobachtet und mittels standardisierter Fragebögen befragt. Ergebnisse Die Haltequote über 2 Jahre betrug 82,3%; nur 4 Patienten beendeten die Behandlung regulär. 25% waren durchgehend frei von Alkohol und Drogen. 25% waren kontinuierlich sozialversicherungspflichtig beschäftigt. Die Mehrheit wies Komorbiditäten sowie Defizite in der sozialen Teilhabe auf. Schlussfolgerung Viele Patienten erreichten Stabilität im Hinblick auf Abstinenz von Suchtmitteln und soziale Teilhabe. Jedoch zeigt eine große Patientengruppe körperliche und psychische Begleiterkrankungen sowie noch erhebliche Defizite in der Teilhabe. Vor allem für diese Patienten erscheint eine zeitliche Limitierung der Substitutionsbehandlung nicht realitätsgerecht.

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Outcomes of Patients in Long-Term Opioid Maintenance Treatment

Cited by 23 publications

References 35 publications

Building abstinent networks is an important resource in improving quality of life

Building abstinent networks is an important resource in improving quality of life

Estimation of the Number of People With Opioid Addiction in Germany

Ergebnisse der langjährigen Substitutionsbehandlung Opiatabhängiger – die SubsCare-Studie

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