Outcomes of Patients with COPD Hospitalized for Coronavirus Disease 2019

Abstract

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Risk of hospitalization in a sample of COVID-19 patients with and without chronic obstructive pulmonary disease

“…For instance, the COPD group was older than the non-COPD group. This finding has been previously reported [ 10 , 40 ], and could be related to older patients with COPD delaying seeking medical help or more comorbidities and severe COPD exacerbations not manageable at home than younger patients [ 41 ]. In order to address the differences among groups, we leveraged multifactor adjustment, which included age in all logistic regression models tested and comorbid diseases in Models 2 and 3.…”

Persistent Steroid Exposure Before Coronavirus Disease 2019 Diagnosis and Risk of Hospitalization in Patients With Chronic Obstructive Pulmonary Disease

“…In a meta-analysis of 15 studies, Alqahtani et al report that only 2% of COVID-19 patients have COPD. 41,42 Multiple studies from the Veterans Affairs (VA) reported a drop in COPD exacerbations during the pandemic, which could reflect masking and social distancing behaviors during the pandemic that prevented infections in this potentially vulnerable population. 43,44 Baum et al reported a 48.4% total reduction in admissions with a principal diagnosis of COPD to the VA in the first 4 months of the pandemic.…”

COVID-19 in Special Patient Groups

“…A meta-analysis stated that a previous history of COPD increases the risk of severe COVID-19 4-fold, and active smoking increases the risk of severe COVID-19 (31). COPD has been associated with a higher need for intensive care, invasive ventilation, and a higher risk of death in patients with COVID-19 (32,33). Patients with COPD presenting with new or increased respiratory symptoms, fever, or other COVID-19 symptoms should be tested for COVID-19, even if they are mild (34).…”