Outcomes of Pulmonary Rehabilitation After Treatment for Non-Small Cell Lung Cancer Stages I to IIIa

Janssen, Steffi; Abbink, Jannie J.; Lindeboom, Robert; Vlieland, Thea Vliet

doi:10.1097/hcr.0000000000000227

Cited by 28 publications

(25 citation statements)

References 8 publications

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“…Fifty patients (stage I-IIIA) started the program with a completion rate of 86%. After 12 weeks, fatigue, QoL, and cardiorespiratory fitness were significantly improved from the baseline assessment [22]. Similarly, other interventional studies showed that EX ameliorates fatigue-related symptoms [24][25][26][27], especially if initiated early after surgery [28].…”

Section: Fatiguementioning

confidence: 70%

“…Similarly, a recent study including patients with surgically resected NSCLC (stage I–II) detected a significant VO 2peak increment in the EX group versus control . Globally considered, although some studies did not report any significant change in functional capacity following a training period , the majority agreed on the potential beneficial effect of exercise on cardiorespiratory fitness .…”

Section: Investigated Outcomes In Lung Cancermentioning

confidence: 98%

See 1 more Smart Citation

Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled?

Avancini

Sartori

Gkountakos³

et al. 2019

The Oncologist

124

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Lung cancer remains the leading cause of cancer‐related death worldwide. Affected patients frequently experience debilitating disease‐related symptoms, including dyspnea, cough, fatigue, anxiety, depression, insomnia, and pain, despite the progresses achieved in term of treatment efficacy. Physical activity and exercise are nonpharmacological interventions that have been shown to improve fatigue, quality of life, cardiorespiratory fitness, pulmonary function, muscle mass and strength, and psychological status in patients with lung cancer. Moreover, physical fitness levels, especially cardiorespiratory endurance and muscular strength, are demonstrated to be independent predictors of survival. Nevertheless, patients with lung cancer frequently present insufficient levels of physical activity and exercise, and these may contribute to quality of life impairment, reduction in functional capacity with skeletal muscle atrophy or weakness, and worsening of symptoms, particularly dyspnea. The molecular bases underlying the potential impact of exercise on the fitness and treatment outcome of patients with lung cancer are still elusive. Counteracting specific cancer cells’ acquired capabilities (hallmarks of cancer), together with preventing treatment‐induced adverse events, represent main candidate mechanisms. To date, the potential impact of physical activity and exercise in lung cancer remains to be fully appreciated, and no specific exercise guidelines for patients with lung cancer are available. In this article, we perform an in‐depth review of the evidence supporting physical activity and exercise in lung cancer and suggest that integrating this kind of intervention within the framework of a global, multidimensional approach, taking into account also nutritional and psychological aspects, might be the most effective strategy. Implications for Practice Although growing evidence supports the safety and efficacy of exercise in lung cancer, both after surgery and during and after medical treatments, most patients are insufficiently active or sedentary. Engaging in exercise programs is particularly arduous for patients with lung cancer, mainly because of a series of physical and psychosocial disease‐related barriers (including the smoking stigma). A continuous collaboration among oncologists and cancer exercise specialists is urgently needed in order to develop tailored programs based on patients’ needs, preferences, and physical and psychological status. In this regard, benefit of exercise appears to be potentially enhanced when administered as a multidimensional, comprehensive approach to patients’ well‐being.

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Section: Fatiguementioning

confidence: 70%

Section: Investigated Outcomes In Lung Cancermentioning

confidence: 98%

Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled?

Avancini

Sartori

Gkountakos³

et al. 2019

The Oncologist

124

View full text Add to dashboard Cite

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“…Regarding the secondary aims, total PA and light PA increased, and percentage of sedentary time diminished, both in IMT and EMT groups, being the effect size higher in the IMT group. After lung resection with or without adjuvant therapy patients experience reduced PA, persistent fatigue, exercise intolerance, depression and loss of QoL [32].…”

Section: Ucare (N = 19)mentioning

confidence: 99%

Influence of Respiratory Muscle Training on Patients’ Recovery after Lung Resection

et al. 2020

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This prospective experimental study aimed to compare effects of 3 different home-based postoperative respiratory muscle training protocols – inspiratory, expiratory and combined, in the patients’ postoperative recovery, regarding safety and respiratory muscle function, pulmonary function, physical fitness, physical activity (PA), dyspnoea and quality of life (QoL). Patients were divided in four groups Usual Care (UCare), inspiratory (IMT), expiratory (EMT) or combined muscle training (CombT) according to group allocation. Significant treatment*time interactions were found for maximal inspiratory pressure (MIP) (p=0.014), sedentary PA (SEDPA) (p=0.003), light PA (LIGPA) (p=0.045) and total PA (p=0.035). Improvements were observed for MIP in CombT (p=0.001), IMT (p=0.001), EMT (p=0.050). SEDPA reduced in EMT (p=0.001) and IMT (p=0.006), while LIGPA increased in both groups (p=0.001), as well as Total PA (p=0.005 and p=0.001, respectively). In UCare, CombT, and EMT, QoL improved only for Usual Activities. In conclusion, the addition of respiratory muscle training to physiotherapy usual care is safe and effective to increase MIP and contribute to improve physical activity. The CombT showed greater improvement on MIP, while IMT compared to EMT, was more effective to improve physical activity.

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“…La persistencia de la fatiga posterior al tratamiento es común en estos pacientes, llevándolos a un ciclo vicioso de inactividad y desacondicionamiento, lo que impide la recuperación del tratamiento (8).…”

Section: Carga Del Cáncer Pulmonar En La Calidad De Vida Y La Capacidunclassified

“…Un estudio observacional de 12 semanas de rehabilitación pulmonar tuvo efectos positivos en la fatiga de aquellos pacientes con cáncer pulmonar de células no pequeñas en estadio I a IIIa tratados de manera curativa con cirugía. Se encontró una mejoría en la calidad de vida y capacidad de ejercicio pico, así como también una reducción significativa de la fatiga (8).…”

Section: Rehabilitación Pulmonar Después De La Cirugíaunclassified

Rehabilitación pulmonar en cáncer pulmonar

Chockee¹,

García²

2019

rev. colomb. neumol.

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El cáncer pulmonar es una enfermedad que conlleva una enorme carga económica y social. La rehabilitación pulmonar ha surgido como una intervención costo-efectiva y ha demostrado mejorar la capacidad de ejercitarse, los síntomas y la calidad de vida en aquellos con enfermedades pulmonares crónicas, principalmente la enfermedad pulmonar obstructiva crónica (EPOC). Hay un mayor reconocimiento de que la rehabilitación pulmonar puede beneficiar a otras condiciones respiratorias como el cáncer pulmonar primario y metastásico a pulmón, en el cual se han documentado efectos positivos en los pacientes; sin embargo, su rol en el ámbito del tratamiento integral no ha sido bien descrito debido a investigaciones limitadas hasta la fecha.La rehabilitación pulmonar ha demostrado en pacientes con cáncer pulmonar mejorar la fuerza, la resistencia y la capacidad de ejercitarse en cualquier estadio de la enfermedad. El componente de entrenamiento de la rehabilitación en el preoperatorio y postoperatorio mejora el consumo de oxígeno preoperatorio, la capacidad de ejercitarse y la calidad de vida; y reduce los síntomas, las complicaciones postoperatorias y la duración de la estancia hospitalaria.En los pacientes que son candidatos a manejo quirúrgico aún no se ha establecido el tiempo óptimo para iniciar la rehabilitación pulmonar ni la duración del programa, pero al- gunos estudios han mostrado que un programa de 4 a 6 semanas prepara adecuadamente para la cirugía a aquellos pacientes con cáncer pulmonar y EPOC, reduciendo las limitaciones funcionales.Los cuidados paliativos son un abordaje comprensivo a largo plazo que puede ser pa- ralelo o integrado al tratamiento del cáncer, mientras que la rehabilitación pulmonar es una estrategia que impacta desenlaces específicos.

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Outcomes of Pulmonary Rehabilitation After Treatment for Non-Small Cell Lung Cancer Stages I to IIIa

Abstract: Rehabilitation after treatment for NSCLC stages I to IIIa showed promising improvements regarding patient fatigue, QoL, and exercise capacity. PR should be considered for patients after treatment for NSCLC stages I to IIIa.

Cited by 28 publications

References 8 publications

Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled?

Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled?

Influence of Respiratory Muscle Training on Patients’ Recovery after Lung Resection

Rehabilitación pulmonar en cáncer pulmonar

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