Outcomes of surgical interventions for primary childhood glaucoma in Northern Tanzania

Fieß, Achim; Furahini, Godfrey; Bowman, Richard; Bauer, Jacqueline; Dithmar, Stefan; Philippin, Heiko

doi:10.1136/bjophthalmol-2015-308137

Cited by 6 publications

(11 citation statements)

References 18 publications

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“…25 Some studies reported lower success rates of angle-based surgeries in PCG, ranging from 30% to 52% at 12 months, possibly because of the higher proportion of severe cases. 14,22 TSCPC demonstrated significantly lower success rates than other procedures (26.7% at 1 y and 20% at 3 y), which is slightly higher than a previously reported success rate of primary TSCPC in PCG patients (17% at 1 y). 14 TSCPC is typically reserved for refractory cases because of its unpredictability of IOP reduction effect and associated serious complications.…”

Section: Discussioncontrasting

confidence: 62%

“…Goniotomy has been shown to have comparable success rates to trabeculotomy 14. The reported success rates for single goniotomy in PCG patients varied between 38% and 75% 14,23–25.…”

Section: Discussionmentioning

confidence: 99%

“…Other studies have reported a wide range of success rates ranging from 30.0% to 92.3%. [14][15][16][17] The use of mitomycin-C was found to improve success of trabeculectomy but associated with increased incidence of complications. [18][19][20] Despite higher success at intermediate term, our study found that primary trabeculectomy had a higher rate of early hypotony and related complications compared with rates reported from previous studies (6.1% to 12.1%).…”

Section: Discussionmentioning

confidence: 99%

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Outcomes of Surgical Interventions in Primary Congenital Glaucoma Patients

Suvannachart

Surukrattanaskul

Chansangpetch

et al. 2022

Journal of Glaucoma

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Purpose: The aim was to report long-term surgical success of primary congenital glaucoma (PCG) patients in Thailand. Materials and Methods: PCG patients who underwent one of the following primary operations: trabeculotomy, goniotomy, trabeculectomy, combined trabeculotrabeculectomy (CTT) and diode transscleral cyclophotocoagulation (TSCPC) between January 1992 and January 2018 were reviewed. Surgical success was defined as intraocular pressure (IOP) between 5 and 21 mm Hg with or without antiglaucoma medications. Failure was defined as IOP ≤5 or ≥21 mm Hg for 2 consecutive visits, or when an additional glaucoma surgery was required to control IOP. Survival curves were analyzed using multilevel mixed-effect Weibull model. Results: A total of 81 eyes from 55 PCG patients were included. Surgical procedures involved 20 goniotomies, 15 trabeculotomies, 16 trabeculectomies, 15 CTT, and 15 TSCPC. Median follow-up time was 24 months (interquartile range: 9 to 60 mo). Overall success rates were 68.8% at 1 year, 63.8% at 3 years, and 53.7% at 5 years. All types of surgery except TSCPC had comparable cumulative 1 year success rates ranging from 78.5% to 83.3%. Cumulative success rates of trabeculotomy (80.05%) and CTT (79.4%) were maintained at 3 and 5 years and were the highest among all procedures at 5 years. TSCPC had a significantly lower success rate compared with other types of surgery (hazard ratio: 7.4 to 13.1, all P=0.01). All patients receiving primary TSCPC showed no success at 48 months. Conclusion: Primary trabeculotomy and primary CTT demonstrated the highest long-term success rates in PCG patients.

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Section: Discussioncontrasting

confidence: 62%

“…Goniotomy has been shown to have comparable success rates to trabeculotomy 14. The reported success rates for single goniotomy in PCG patients varied between 38% and 75% 14,23–25.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Outcomes of Surgical Interventions in Primary Congenital Glaucoma Patients

Suvannachart

Surukrattanaskul

Chansangpetch

et al. 2022

Journal of Glaucoma

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“…15 A comparable pre-operative intraocular pressure of 33.1 ± 10.2 mm Hg was observed in another study done in Northern Tanzania. 16 The procedure was found successful in 55(84.6%) out of 65 of our patients at the end of three months. A previous study on 196 eyes, operated for congenital glaucoma with goniotomy, reported a similar 80% success rate.…”

Section: Discussionmentioning

confidence: 56%

“…A study conducted in Northern Tanzania showed a success rate of 38% at 12 months follow up. 16 Another study showed a success rate of 50.6% in children undergoing goniotomy for primary paediatric glaucoma conducted by Hassan ein et al 19 The differences in the success rate of goniotomy in different studies may be due to factors like different follow-up period, patient compliance, socioeconomic status, the underlying cause for glaucoma and ethnicity.…”

Section: Discussionmentioning

confidence: 99%

Success Rate of Goniotomy in Terms of Intraocular Pressure Control in Pediatric Glaucoma Patients

Hussain

Mahmood

2022

PAFMJ

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Objective: To determine the success rate of goniotomy in terms of reduction in intraocular pressure. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Ophthalmology, at Faisalabad Medical University/Allied Hospital Faisalabad from Apr 2016 to Aug 2017. Methodology: A total of 65 patients were enrolled in our study. The patients with intraocular pressure greater than 21 mm Hg and corneal diameter less than 13 millimetres were included. Intraocular pressure was measured before and four-weeks after goniotomy. Intraocular pressure measurement of less than 21 mm Hg four- weeks after surgery was considered successful. Results: Out of 65 patients, 35 (53.8 %) were male, and 30 (46.2%) were female. The age of patients ranged from 3 months to 33 months, with a mean age of 15.25 ± 7.66 months. Among 65 patients operated for goniotomy, the procedure was found successful in 55 (84.6%) patients, and only 10 (15.4%) patients did not show improvement following goniotomy. The fall in intraocular pressure from baseline to post-operative values of intraocular pressure was statistically significant (p-value < 0.01). Conclusions: Goniotomy is an effective procedure for lowering intraocular pressure in childhood glaucoma patients and can be offered as a primary and initial procedure at an early age.

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Childhood Glaucoma Surgery in Developing Countries

Mandal

Senthil

2018

Surgical Management of Childhood Glaucoma

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Outcomes of surgical interventions for primary childhood glaucoma in Northern Tanzania

Cited by 6 publications

References 18 publications

Outcomes of Surgical Interventions in Primary Congenital Glaucoma Patients

Outcomes of Surgical Interventions in Primary Congenital Glaucoma Patients

Success Rate of Goniotomy in Terms of Intraocular Pressure Control in Pediatric Glaucoma Patients

Childhood Glaucoma Surgery in Developing Countries

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