Outcomes of Trimodality Approach in the Management of T2N0M0 Bladder Cancer

Abstract

Bladder preserving approach is an alternative definitive therapy solution to radical cystectomy in the treatment of muscle-invasive bladder cancer with less morbidity, preserved natural bladder, and high quality of life.

Bladder sparing surgery in high-grade bladder cancer

“…It includes transurethral resection of all visible bladder tumor and postoperative chemo-radiotherapy [9][10][11][12]. The reported success rates of this trimodality treatment is compared or even higher than that of RCE, which makes it a viable alternative [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. Nevertheless, mentioned trimodality approach possesses one significant disadvantage, namely, high local recurrence rate, which is estimated in the range of 30-70% of cancer persistence during repeated TURB [7].…”