2021
DOI: 10.1016/j.jamcollsurg.2021.03.002
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Outcomes of Vascularized Lymph Node Transplantation for Treatment of Lymphedema

Abstract: BACKGROUND: A growing body of evidence supports the efficacy of surgical treatments for lymphedema. This study reports the outcomes of vascularized lymph node transplantation (VLNT) for the treatment of patients with lymphedema compared with maximal conservative treatment alone. STUDY DESIGN: Consecutive patients undergoing VLNT to treat primary and secondary lymphedema affecting the upper or lower extremities were included. All patients were optimized … Show more

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Cited by 27 publications
(25 citation statements)
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“…VLNT, on the other hand, is likely responsible for the delayed, sustained improvements seen more than 2 years postoperatively, as its mechanism of action requires more time for optimal functioning. Similar findings have been subsequently published by others [ 6 ].…”
Section: Combined Surgeriessupporting
confidence: 92%
“…VLNT, on the other hand, is likely responsible for the delayed, sustained improvements seen more than 2 years postoperatively, as its mechanism of action requires more time for optimal functioning. Similar findings have been subsequently published by others [ 6 ].…”
Section: Combined Surgeriessupporting
confidence: 92%
“…on VLNT which report significant improvements in limb circumference or volume, QOL, cellulitis, and compression. 25,[29][30][31][32][33][34][35][36][37][38][39][40] While these results appear positive across the board, they do not reflect the consensus of the lymphatic surgery community: VLNT does work but not everyone experiences an improvement. It is difficult to obtain a clear picture of the outcomes of VLNT because current publications focus on mean and standard deviation, and outcomes do not always follow a standard distribution.…”
Section: Discussionmentioning
confidence: 99%
“…68 VLNT has also been shown to improve patient-reported outcomes and improve limb function measures. [67][68][69] More recently, some have argued for simultaneous VLNT and LVB with studies demonstrating improved volume reduction and quality of life for both early and advanced secondary lymphedema. 57…”
Section: Vascularized Lymph Node Transplantmentioning
confidence: 99%