Background: Urinary incontinence (UI) subtypes often differ by symptom severity and treatment profiles; in particular, mixed UI is generally associated with worse symptoms and less successful treatment. Yet, limited information exists on the natural history of different urinary incontinence (UI) subtypes, which could help better identify and treat patients prior to development of more intractable disease.Objective: To evaluate the onset of UI subtypes, and transitions between subtypes over 8 years, using two large cohorts of middle-age and older women with incident UI.
Study Design:We identified 10,349 women with incident UI (stress, urgency, and mixed subtypes), from the Nurses' Health Study and Nurses' Health Study II, age 41-83 years, using repeated mailed questionnaires. We defined stress UI as leakage with coughing, sneezing, or activity; urgency UI as urine loss with a sudden feeling of bladder fullness or when a toilet was inaccessible; and mixed UI when women reported that stress and urgency symptoms occurred