Outpatient initiation of long‐term continuous positive airway pressure in children

Amaddeo, Alessandro; Frapin, Annick; Touil, Samira; Khirani, Sonia; Griffon, Lucie; Fauroux, Brigitte

doi:10.1002/ppul.24138

Cited by 40 publications

(43 citation statements)

References 32 publications

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“…All pts were started on ventilation as in‐pts, most of them (83%) in the general pediatric ward. Two groups have published outpatient long‐term ventilation initiation experience and compared them to in patient experience with promising results 25,26 . As stated before, lack of bed availability for family NIV training explains the delay in ventilation start.…”

Section: Discussionmentioning

confidence: 99%

Feasibility of a pediatric long‐term Home Ventilation Program in Argentina: 11 years' experience

Leske

Guerdile

González

et al. 2020

Pediatric Pulmonology

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Background Pediatric home ventilation (HV) has increased worldwide. A Home Ventilation Program (HVP) was started in the Pulmonary Department of the “Hospital de Pediatría Prof. Dr. J. P. Garrahan,” Argentina, in 2007. This is the largest Argentine national pediatric tertiary care referral center. Limited studies on pediatric HV from Latin American countries have been published. Objective This study describes and analyzes the cohort of children admitted to the HVP during an 11 years period. Methods Longitudinal study. Population: all patients (pts) admitted to the HVP between 2007 and 2018. We analyzed demographic and clinical variables, sleep study results, ventilation setting, and start manner collected in a prospective data base. Results A total of 244 pts were admitted. Median age at ventilation start was 9.41 (3.47‐14.08) years, 84% of pts had health insurance. The most frequent underlying diseases were neuromuscular disease (43%) and genetic syndromes (23%). Home‐hospital distance was 100‐500 km in 16% of cases and greater than 500 km in 34%. Seventy percent of pts had sleep studies before ventilation initiation. Ventilation was started in our general pediatric ward in 83.6%. Noninvasive ventilation was used in 86.1%. The actual number of pts still on follow up is 133 of 244 (54.5%), 16.8% dropped out, 16.4% were transitioned to adult care, 5.32% resolved their sleep‐disordered breathing, and 5.32% died. Conclusions The HVP admitted pts from all the country. Ventilation was started on the basis of clinical and objective sleep measures. This long‐term experience underlines the feasibility of a HVP in an emergent country.

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Section: Discussionmentioning

confidence: 99%

Feasibility of a pediatric long‐term Home Ventilation Program in Argentina: 11 years' experience

Leske

Guerdile

González

et al. 2020

Pediatric Pulmonology

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“…CPAP was changed for NIV in case of persistent oxygen desaturations and/or hypercapnia despite the highest tolerated CPAP pressure and/or in case of nocturnal hypoventilation without respiratory events (Kushida et al, ). CPAP/NIV initiation was performed within a specific therapeutic education program adjusted on mental age, cognition, and cooperation (Amaddeo et al, ). The therapeutic education tools integrated booklets, a teddy bear breathing with NIV, and playful evaluation tools (see http://vnietsommeil.aphp.fr).…”

Section: Methodsmentioning

confidence: 99%

A retrospective study on sleep‐disordered breathing in Morquio‐A syndrome

Facchina

Amaddeo

Baujat

et al. 2018

American J of Med Genetics Pt A

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Respiratory problems are common in Morquio-A syndrome (MPS IVA) but objective data on sleep-disordered breathing are scarce. The aim of our study was to review polygraphic (PG) findings and the need for noninvasive continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in children with MPS IVA. A retrospective review of the clinical charts and PG of 16 consecutive children (7 boys, mean age 10.5 AE 4.2 years) with MPS IVA seen over a period of 3 years was performed. The prevalence of obstructive sleep apnea (OSA) was 69% with only five patients, all younger than 10 years old, having a normal PG. Four patients had mild OSA (apnea-hypopnea index [AHI] ≥1.5 and <5 events/hr), three patients had moderate OSA (AHI ≥5 and <10 events/hr), and three patients had severe OSA (AHI ≥ 10 events/hr). Among the 10 patients with OSA, 3 had prior adenoidectomy AE tonsillectomy and 6 were on enzyme replacement therapy. Only one patient had a central apnea index >5 events/hr despite prior cervico-occipital decompression. Six patients, all older than 11 years old, were started on CPAP or NIV because of severe OSA (n = 4), nocturnal hypoventilation (n = 1), or impossibility to be weaned from NIV after an acute respiratory failure (n = 1). Prevalence of OSA is high in patients with MPS IVA, underlying the importance of a systematic screening for sleep-disordered breathing. CPAP and NIV are efficient and well accepted for treating sleep-disordered breathing.

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“…CPAP was use was better if another family member was also on CPAP, obesity did not affect CPAP adherence ( 41 ). Amaddeo et al ( 42 ) studied out-patient initiation of CPAP therapy in children and showed a general high level of adherence in their cohort of 31 children (3 were obese).…”

Section: Cpap In Obese Childrenmentioning

confidence: 99%

Long Term Continuous Positive Airway Pressure and Non-invasive Ventilation in Obstructive Sleep Apnea in Children With Obesity and Down Syndrome

Verhulst

2020

Front. Pediatr.

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This review will focus on non-invasive ventilation (NIV) and continuous positive airway pressure (CPAP) therapy in children with obstructive sleep apnea (OSA) due to obesity and underlying syndromes. These children have a high prevalence of OSA and residual OSA after adenotonsillectomy. Therefore, a high proportion of these children are treated with CPAP or NIV. This review will focus on treatment selection tools and will subsequently cover specific issues on CPAP treatment in obese and syndromic children with a major focus on Down syndrome.

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Outpatient initiation of long‐term continuous positive airway pressure in children

Abstract: Initiating CPAP in an outpatient setting in children is feasible and effective in selected subjects. A high rate of compliance can be achieved as well as a correction of OSA.

Cited by 40 publications

References 32 publications

Feasibility of a pediatric long‐term Home Ventilation Program in Argentina: 11 years' experience

Feasibility of a pediatric long‐term Home Ventilation Program in Argentina: 11 years' experience

A retrospective study on sleep‐disordered breathing in Morquio‐A syndrome

Long Term Continuous Positive Airway Pressure and Non-invasive Ventilation in Obstructive Sleep Apnea in Children With Obesity and Down Syndrome

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