Outpatient parenteral antimicrobial therapy with ceftriaxone, a review

Duncan, Christopher; Barr, David; Seaton, R Andrew

doi:10.1007/s11096-012-9637-z

Cited by 44 publications

(23 citation statements)

References 71 publications

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“…However, it was mainly used for more serious infections such as soft tissue sepsis. Cure rates exceeding 90% in other OPAT services, were also previously reported [15,16].…”

Section: Discussionsupporting

confidence: 58%

Outpatient Parenteral Antimicrobial Therapy (OPAT) in the Kingdom of Bahrain: Efficacy, Patient Satisfaction and Cost Effectiveness

Ansari¹

2013

TOIDJ

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Outpatient parenteral antimicrobial therapy (OPAT) is an alternative method to deliver intravenous antimicrobial agents to patients requiring parenteral therapy without an overnight hospital stay. The aim of this study was to review the OPAT services, to explore patient satisfaction with the services provided, and to determine cost effectiveness. A retrospective review for the raw data collected in the OPAT clinic between February 2012 and January 2013 was included. Patients' variables including age, sex, type of infection, and service costs were analyzed with descriptive statistics. Each patient's eligibility was assessed by an infectious disease physician (ID), and a family physician. Patient's satisfaction was measured by a modified short version patient satisfaction questionnaire. Cost was calculated for each patient in the OPAT clinic and compared to the actual cost if the same patient was admitted and treated in the hospital. During the last 12 months, 101 patients, 92 adults, and nine children were treated in our OPAT clinic. Half (50%) of the patients were referred from general practitioner services and our emergency department. Ceftriaxone was the most frequently used antibiotic, prescribed to 76% of the patients. Successful cure was achieved in 97 treated patients. Patients were highly satisfied with the OPAT service with the mean rating of 4.41 SD + 0.31. Cost was reduced from $75, 000 to $30, 000 over one year. This retrospective study suggested that OPAT service is safe and potentially a cost saving approach for the health care system. OPAT service is acceptable and well tolerated among patients receiving intravenous antimicrobial agents.

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“…However, it was mainly used for more serious infections such as soft tissue sepsis. Cure rates exceeding 90% in other OPAT services, were also previously reported [15,16].…”

Section: Discussionsupporting

confidence: 58%

Outpatient Parenteral Antimicrobial Therapy (OPAT) in the Kingdom of Bahrain: Efficacy, Patient Satisfaction and Cost Effectiveness

Ansari¹

2013

TOIDJ

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“…This represents a departure from more frequent inpatient regimens, such as flucloxacillin and penicillin, and the risks of broad‐spectrum antibiotics need to be balanced against the risks of hospital admission. Certainly, ceftriaxone seems to be effective in skin/soft tissues infections and pneumonia with low complication rates . HITH may also be used to support children with chronic or developmental conditions presenting to ED to avoid a hospital admission.…”

Section: Hospital‐in‐the‐homementioning

confidence: 99%

Alternatives to ward admission from the emergency department

Bryant

Hopper

2016

J Paediatrics Child Health

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There is ever-increasing pressure on hospital resources in general and emergency departments (ED) in particular. At the same time, there is increasing recognition that traditional inpatient ward-based care is not necessary for the majority of children presenting to the ED with acute illness, and that there are patient, family and hospital benefits to pursuing other options. Here, we describe alternative pathways for children presenting to the ED, including short stay and observational medicine, hospital-in-the-home and non-admission enhanced care, in other words, additional management practices or pathways for children who are discharged from the ED. We discuss the principles, models and practical considerations involved in each of these.

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“…Yarı ömrü 8-12 saat gibi uzundur; kas içi de uygulanabilir. Bu özel-likleri ile ayaktan parenteral antibiyotik tedavisi (APAT) uygulamasına uygundur (7) . Güvenilirlik profili net olarak bilinmektedir.…”

Section: Günümüzde Sefalosporinler Ve Antibiyotik Direnciunclassified