Ovarian and adrenal vein steroids in patients with nonneoplastic hyperandrogenism: selective catheterization findings

Moltz, L.; Schwartz, U.; Sörensen, R.; Pickartz, H; Hammerstein, J.

doi:10.1016/s0015-0282(16)47960-4

Cited by 54 publications

(29 citation statements)

References 12 publications

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“…Specificity tends to be 100%, but with a sensitivity of about 70%, not all adrenocortical tissue tumors can be identified (11). In our case the use of this method failed to reveal uptake of the nuclide by the tumor.…”

Section: Discussioncontrasting

confidence: 57%

Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle

Mavroudis¹,

Aloumanis²,

Papapetrou³

et al. 2007

Fertility and Sterility

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Section: Discussioncontrasting

confidence: 57%

Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle

Mavroudis¹,

Aloumanis²,

Papapetrou³

et al. 2007

Fertility and Sterility

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“…The SHBG levels are reduced. The selective catheterization of the ovarian and adrenal veins, as well as test stimulators and inhibitors specific for adrenal and ovary, have revealed that the adrenal gland is the main source of DHEA and DHEAS , while the major contribution to the production of T, D4-A and 17-hydroxyprogesterone (17-OH-P) comes from the ovary, in agreement with the high enzymatic activity of the P450c17 at the theca cells level [56]. The quantity of free testosterone (T) or the index of free T (free androgen index, FAI) are the most sensitive methods to assess the hyperandrogenemia [57].…”

Section: Diagnostic Criteria In Hyperandrogenism In Pcosmentioning

confidence: 63%

Polycystic Ovary Syndrome: Features, Diagnostic Criteria and Treatments

G¹

2014

Endocrinol Metab Synd

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Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorder that affects 6-15% of the female population. It is a very complex syndrome that involves the hypothalamus, the pituitary gland, the ovaries, the adrenal gland and the peripheral adipose tissue that together contribute to create a generally imbalance, associated with three characteristic symptoms: oligo-anovulation, hirsutism and infertility. PCOS has been studied over a prolonged period of time and yet is still not fully understood. In

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“…Data for testosterone and androstenedione gradients found in 8 healthy women [4] served as controls. The upper 95% confidence limit of the ovarian-peripheral gradient for testosterone is 0.21 ng/ml [5). Unilateral elevation of the ovarian-peripheral gradient for testosterone (> 2.7 ng/ml) is indicative of tumor development and justifies surgical exploration of the ovary [3].…”

Section: Methodsmentioning

confidence: 99%

Nonneoplastic Gonadal Testosterone Secretion as a Cause of Vaginal Cell Maturation in Streak Gonad Syndrome

Bösze¹,

Számel

Molnár

et al. 1986

Gynecol Obstet Invest

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Endocrine studies were carried out on 3 patients with streak gonad syndrome, 2 of whom had slight proliferative vaginal smear patterns, and the 3rd had slight hirsutism with increased muscle mass but an atrophic type vaginal smear pattern. Simultaneous sampling of peripheral, adrenal and streak gonadal venous blood revealed mildly increased testosterone secretion by the streaks in the 2 patients who had proliferative cytohormonal patterns. Histologic examination of their streak gonads showed hilus cell hyperplasia. It might be suggested that hilus cell hyperplasia was the source of the increased testosterone secretion in these 2 patients and thus resulted in slight maturation of the vaginal epithelium.

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Ovarian and adrenal vein steroids in patients with nonneoplastic hyperandrogenism: selective catheterization findings

Cited by 54 publications

References 12 publications

Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle

Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle

Polycystic Ovary Syndrome: Features, Diagnostic Criteria and Treatments

Nonneoplastic Gonadal Testosterone Secretion as a Cause of Vaginal Cell Maturation in Streak Gonad Syndrome

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