Ovarian Cryopreservation: An Overview of Current Evidence around the Globe

Abstract

Advancements in cancer as well as, autoimmunological or hematological conditions treatment have significantly increased the survival rate as well as, the Quality of Life (QoL) for these patients. In addition, Assisted Reproductive Techniques (ART) offers a variety of therapeutic approaches that aim towards fertility preservation and hormonal restoration after treatment. Ovarian Tissue Cryopreservation (OTC) and Ovarian Tissue Transplantation (OTT) have been proposed as an efficient alternative to reserve fertility and hormona function in cases of prepubertal young girls and women needed to be treated immediately with radiation and/or chemotherapy. In this narrative review, current scientific evidence is summarized in order to explore OTC/OTT. In addition to the qualitive presentation of our findings, we provide cumulative evidence from other published studies to demonstrate the clinical potential and limitations of these procedures.

Fertility preservation in patients with endometriosis: Realistic approach or Future fantasy?

“…98 In a previous publication, we reviewed current evidence of OTC-OTT, however our search retrieved findings based on oncologic patients, prepubertal girls and other groups of patients with diseases such as haematologic and autoimmune conditions that required immediate gonadotoxic treatment, thus OTC-OTT was at the time an optimal fertility preservation option. 99,100…”