Ovarian granulosa cell tumor in a Persian cat: Case report from Tripoli, Libya

Abstract

Backgroundː Ovarian granulosa cell tumors (GCTs) are common neoplasms in domestic animals that originate from the sex-cord stromal cells of the ovary. The aim of the present paper was to report a case of ovarian granulosa cell tumor in a 5- year- old Persian female cat and to describe the histopathological pattern of this tumor. Case Descriptionː The cat was brought for a routine diagnostic examination for pregnancy at Albaittar clinic in Tripoli, Libya with a history of one month mating before it was brought to the clinic for investigation of progressive behavioral changes. The cat external examination showed noticeable enlargement at the abdomen that was potentially suspected for pregnancy; however, the abdominal ultrasonography showed a great mass located on right ovary. Therapeutic ovariohysterectomy was performed. The cat’s clinical signs resolved, 6 months later it was diagnosed with a mass on the right kidney suspected as metastasis and one week later the cat died. Conclusion: In this case, macroscopic and microscopic studies are discussed and histopathological examination confirmed ovarian granulosa cell tumor with cystic endometrial hyperplasia and suspected metastasis in one kidney.

WSAVAguidelines for the control of reproduction in dogs and cats

“…As in dogs, non‐regenerative anaemia due to oestrogen‐induced bone marrow toxicity, uterine disease (CEH) and increased susceptibility to infections, among others pyometra, may occur in female cats (Axner, 2010). Ovarian neoplasms are rare in cats and mostly occur in cats >10 years of age (McEntee, 2002; Norris et al., 1969); however, a granulosa cell tumour (GCT) was diagnosed in a 5‐year‐old female cat (Elbahi et al., 2022). Tumour types are the same in dogs and cats (Gelberg & McEntee, 1985; Nielsen et al., 1976; Norris et al., 1970).…”