Ovarian Lipoleiomyoma: A Rare Entity

Abstract

Ovarian lipoleiomyoma is an extremely rare neoplasm and may pose a diagnostic challenge for clinicians, radiologists, and pathologists. It is rarely described as case reports in the literature; almost all patients are late middle aged or elderly. Hereby, we encountered a 57-yr-old postmenopausal woman who presented with abdominal pain. Radiologic investigation revealed a heterogenous nonenhancing mass in the left adnexa, suggestive of dermoid cyst. Microscopic examination showed clusters of adipocytes intersecting the fascicles of smooth muscles, diagnostic of lipoleiomyoma. The present case revisits the clinical and morphologic findings of lipoleiomyoma along with previously published cases in literature.

Primary Ovarian Lipoleiomyoma with Chondroid Metaplasia: an Original Case Report with Literature Review

“…Clinically primary leiomyoma of the ovary is usually asymptomatic due to its small size (< 3cm), hence discovered accidentally either during routine surgery or autopsy, while larger ones are symptomatic presented with abdominal pain, palpable lump, hydronephrosis, and Meig's syndrome [2,8]. In 1989, Dodd et al were the rst person who described the Primary lipoleiomyoma of the ovary [9].Till date, only 5 cases of primary ovarian lipoleiomyoma are reported; the majority of them were in the fth to sixth decade of life, while in our index case, the patient's age is 22 years (Table-1) [4,6,[9][10][11]. Clinically, the tumor was diagnosed incidentally or presented with painless mass or abdominal pain [6, 9, 10].…”

“…Clinically, the tumor was diagnosed incidentally or presented with painless mass or abdominal pain [6, 9, 10]. An occasional case had post-menopausal spotting as a presenting complaint [4]. The size of the tumor varies from 6 cm to 26 cm on its longest axis [4,6,[9][10][11].…”

“…In the brief English literature reviewed, not more than 100 cases of primary ovarian leiomyoma have been reported [2,3]. Primary ovarian lipoleiomyoma is even more sparse, and only 5 case reports have been published till date [4]. Usually, primary ovarian leiomyoma is asymptomatic and is seen mostly in premenopausal women [5].…”

Primary ovarian lipoleiomyoma with chondroid metaplasia: an original case report with literature review

“…Clinically primary leiomyoma of the ovary is usually asymptomatic due to its small size (< 3cm), hence discovered accidentally either during routine surgery or autopsy, while larger ones are symptomatic presented with abdominal pain, palpable lump, hydronephrosis, and Meig's syndrome [2,8]. In 1989, Dodd et al were the rst person who described the Primary lipoleiomyoma of the ovary [9].Till date, only 5 cases of primary ovarian lipoleiomyoma are reported; the majority of them were in the fth to sixth decade of life, while in our index case, the patient's age is 22 years (Table-1) [4,6,[9][10][11]. Clinically, the tumor was diagnosed incidentally or presented with painless mass or abdominal pain [6, 9, 10].…”

“…In the brief English literature reviewed, not more than 100 cases of primary ovarian leiomyoma have been reported [2,3]. Primary ovarian lipoleiomyoma is even more sparse, and only 5 case reports have been published till date [4]. Usually, primary ovarian leiomyoma is asymptomatic and is seen mostly in premenopausal women [5].…”