Ovarian Pregnancy Following in Vitro Fertilization in a Woman After Bilateral Salpingectomy: A Case Report and Review of the Literature

Case Report of Ectopic Ovarian Pregnancy following Fresh Embryo Transfer

“…Surprisingly, several cases of ovarian pregnancies were described following in vitro fertilization-embryo transfer (IVF-ET) in patients who had previously undergone bilateral salpingectomy. The exact mechanism for these is unclear but should encourage further evaluation of other potential pathophysiological mechanisms for the formation of ovarian pregnancies following fresh and frozen embryo transfer 22. An interesting proposed mechanism was described by Shan et al23 According to this suggestion, the cause for ovarian pregnancy is pelvic inflammation that involves the ovary.…”

“…An interesting proposed mechanism was described by Shan et al23 According to this suggestion, the cause for ovarian pregnancy is pelvic inflammation that involves the ovary. Consequently, the inflammation of the ovary may affect the process of detachment of the cumulus-oocyte complex and prevent the release of the ovulated oocyte, leading to fertilization of the mature oocyte by the sperm arriving through the fallopian tube inside the ruptured follicle 22,23. Despite its uncommon occurrence, perhaps ovarian stimulation and the resulting high estradiol concentration as well as the oocyte retrieval induce an inflammatory process in the ovary, which affects the oocyte release.…”

“…The exact mechanism for these is unclear but should encourage further evaluation of other potential pathophysiological mechanisms for the formation of ovarian pregnancies following fresh and frozen embryo transfer. 22 An interesting proposed mechanism was described by Shan et al 23 According to this suggestion, the cause for ovarian pregnancy is pelvic inflammation that involves the ovary. Consequently, the inflammation of the ovary may affect the process of detachment of the cumulus-oocyte complex and prevent the release of the ovulated oocyte, leading to fertilization of the mature oocyte by the sperm arriving through the fallopian tube inside the ruptured follicle.…”

Ovarian Ectopic Pregnancy after Endometriomal Cyst Resection, Following In vitro Fertilization (IVF): A Rare Case Report

“…Hagit Feit et al, reported a case of ovarian EP following IVF in a patient with previous history of bilateral salpingectomy. They believe that the responsible mechanism for ovarian EP in their case was either uterine perforation with the ET catheter and implantation of the embryo on the ovary or a tuboperitoneal fistula and migration of the embryo from this fistula to the ovary [33].…”

“…Preoperative diagnosis of an ovarian EP could be very challenging and is only achieved in 5.3-25% of patients [33,38]. Consequently, the definite diagnosis is only possible during operation.…”