Ovarian sertoliform endometrioid carcinoma: A diagnostic dilemma

Bakshi, Neha; Gupta, Neelam; Mahajan, Vidisha

doi:10.4103/0377-4929.120419

Cited by 5 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bilateral ovarian metastasis of sertoliform endometrioid carcinoma with omental metastasis showed small hollow or solid tubules surrounded by cellular and fibrous stroma. [23][24][25] Immunohistochemistry (Inhibin negative, Estrogen receptor positive and WT1 negative) confirmed the endometrial origin of the tumor and ruled out the sertoli cell tumor in these two cases.Figure 5 6…”

Section: Discussionmentioning

confidence: 82%

Clinicopathological spectrum of ovarian neoplasms in pre and post menopausal Indian women

Bobde

Kawthalkar²,

Kumbhalkar³

2022

ACHR

View full text Add to dashboard Cite

Ovarian cancers are the third most common cancers in women trailing behind cervical and breast cancer. Various molecular insults are seen in hereditary cancer syndromes that results in different morphological types of ovarian cancer.Accurate histological typing suggests screening of the first degree relatives and also targeted therapy for the same. Age specific incidence rate showed that ovarian cancer increases from 35 years of age and peaks between 55 to 64 years of age. Present study was conducted to know the clinical and histopathological spectrum of ovarian neoplasms. To correlate the histopathological subtype with the pre and post menopausal age group. This is a retrospective observational study of 196 cases found over 2.5 years during January 2018 to June 2020. Surface epithelial tumors(SET) are commonest in our study (benign 50%, borderline 6% and malignant 17%) followed by germ cell tumors (12%), sex cord stromal tumors (9%), secondary tumors (5%) and mixed epithelial and mesenchymal tumor (0.5%). Benign SET and germ cell tumors are significantly associated with premenopausal age whereas malignant SET has significant association with post menopausal age. However sex cord stromal tumors did not show any significant association with both the groups. Bilateral involvement was commonest with secondary tumors followed by malignant SET. Mean age of presentation was 41 years with maximum cases presenting in 4 and 5 decade. Various histomorphological parameters were evaluated in detail along with immunohistochemistry(IHC). Inhibin negativity helped to differentiate sertoliform variant of endometrial carcinoma from sertoli cell tumor. WT1 positivity in serous carcinoma ruled out poorly differentiated endometrioid carcinoma in two cases. Thirteen cases show extraovarian spread. Synchronous neoplasms of female genital tract (fibroma with uterine endometrial carcinoma and Brenner with basaloid carcinoma cervix ) were found. Collision tumors (sex cord stromal tumors with germ cell tumors) were also found in present study. Using WHO classification, ovarian tumors can be precisely subcategorized into different morphological subtypes. However overlapping features may need IHC to pinpoint the correct diagnosis. Age specific occurrence of different morphological subtypes may suggest other ancillary investigations and different treatment modalities

show abstract

Section: Discussionmentioning

confidence: 82%

Clinicopathological spectrum of ovarian neoplasms in pre and post menopausal Indian women

Bobde

Kawthalkar²,

Kumbhalkar³

2022

ACHR

View full text Add to dashboard Cite

show abstract

“…Although areas of conventional endometrioid adenocarcinoma are generally present in SEC, there are some cases of SEC where the whole tumor consisted of sex-cord-like areas. [17] Further, cytoplasmic mucin may also be absent in some cases of SEC. [8]…”

Section: Discussionmentioning

confidence: 99%

“…Sertoliform endometrioid carcinoma (SEC) is a rare variant of endometrioid ovarian carcinoma which resembles Sertoli and Sertoli-Leydig cell tumors (SLTs) on histology. [1] This similarity with sex-cord tumors may lead to diagnostic pitfalls. [2] SEC is usually a well-differentiated, low-grade tumor and has a good prognosis when confined to the ovary.…”

Section: Introductionmentioning

confidence: 99%

Sertoliform endometrioid carcinoma of ovary presenting as abdominal wall abscess

et al. 2018

View full text Add to dashboard Cite

Sertoliform endometrioid carcinoma (SEC) is a rare epithelial ovarian cancer which may be mistaken for sex cord tumour on microscopy. Immunohistochemistry and extensive sampling of tumour to look for areas of conventional endometrioid carcinoma are important to confirm the diagnosis of SEC. We report a case of SEC of ovary in a postmenopausal lady who presented to us with abdominal wall abscess in epigastric region.

show abstract

“…Recognition of this tumor is important as it is a well-differentiated, low-grade malignancy that displays a good prognosis when confined to the ovary. [ 1 2 ]…”

Section: Introductionmentioning

confidence: 99%

Sertoliform Endometrioid Tumor of Ovary Presenting as Torsion

et al. 2016

View full text Add to dashboard Cite

Sertoliform endometrioid carcinoma of the ovary (SEC) is an uncommon variant that bears histologic similarity to sertoli and sertoli-leydig cell tumors. We report an interesting case of SEC in a 55-year-old female with a left ovarian mass with torsion. Histology revealed an SEC, featuring foci of typical endometrioid carcinoma, and areas composed of uniform, small, hollow tubules lined by columnar cells with apical cytoplasm. Tumor cells were strongly immunoreactive for EMA and cytokeratin but negative for inhibin; thus, confirming the diagnosis of SEC ovary. Recognition of this tumor is important as it is a well-differentiated, low-grade malignancy that displays good prognosis when confined to the ovary.

show abstract

Ovarian sertoliform endometrioid carcinoma: A diagnostic dilemma

Cited by 5 publications

References 0 publications

Clinicopathological spectrum of ovarian neoplasms in pre and post menopausal Indian women

Clinicopathological spectrum of ovarian neoplasms in pre and post menopausal Indian women

Sertoliform endometrioid carcinoma of ovary presenting as abdominal wall abscess

Sertoliform Endometrioid Tumor of Ovary Presenting as Torsion

Contact Info

Product

Resources

About